ورقة علمية منشورة : Evaluation of the Antimicrobial Potential of Selected Medicinal

Journal Article

Al-Askar, A.A. . 2014

• نوع عمل المنشور: بحث
• المجلة \ الصحيفة: JOURNAL OF PURE AND APPLIED MICROBIOLOGY
• رقم العدد: 1
• رقم الإصدار السنوي: 8
• الصفحات: 159-168

مستخلص المنشور

In vitro antimicrobial activity of methanolic extracts of six medicinal plants

(black seed, camphor, cloocynth, clove, ginger and white cedar) were investigated against

pathogenic bacteria and fungi at 3, 6 and 9% concentrations. Results obtained in this

study showed that the six plant extracts exhibited varied extents of antimicrobial activity

against the tested organisms even at low concentration. Among the tested plant extracts,

ginger recorded the highest antifungal activity against Alternaria radicina, Fusarium

oxysporum, F. solani, Macrophomina phaseolina, Nigrospora oryzae, Phoma destructiva,

Rhizoctonia solani and Sclerotium rolfsii at 9% concentration. Whilst, the maximum

antibacterial activity was achieved by black seed extract at 9% concentration against the

Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) and Grampositive

bacteria (Staphylococcus aureus and Streptococcus pneumonia). Chemical

compositions of ginger and black seed methanolic extracts were studied using GC-MS

analysis and resulted in the identification of 19 and 17 compounds, respectively. Further

studies are needed to investigate the antimicrobial potentiality of the active constituents

singly or in mixtures with other antibiotics.