PHT 434

Sterile Dosage Forms (2+1)

Physicochemical properties as well as the design and formulation of ophthalmics and injectable dosage forms; including isotonicity, acid-base properties as well as sterilization principles and techniques are studied. Basic principles of radiopharmacy and radio- pharmaceuticals are also discussed

 

Topics to be Covered
Topic	No of Weeks	Contact hours
1-      Overview of Sterile Preparation Formulation       Introduction and characteristics of sterile dosage forms	1	1
2-      Sterile preparation formulation              Components, containers and closure	2	1
3-      Parenteral formulations: Vehicles; additive	3	1
4-      Physiological Norms Pyrogenicity Tonicity Particulate matter Stability Storage	4	1
5-      Sterile preparation Facilities and Equipment          Syringes and needles         Ampules or vials         Laminar airflow hoods         Biological Safety Cabinets IV bags	5 6	2
6-      Procedure for Compounding Solutions              IV admixture incompatibility	7 8	2
7-      Methods of sterilization	9 10	2
8-      Ophthalmic preparations	11 12	2
Exams		2