Quinazoline, Pyrazolo[1,5-c]quinazoline and Spiro Quinazoline Dimers from the Reaction of 2-Aminoacetophenene Hydrazones with Triphosgene
Mousa, H. Z. Alkhathlan, M. A. Al-Saad, A. A. . 2002
Abstract
The reaction of hydrazones of 2-aminoacetophenone with triphosgene in dichloromethane or benzene in the presence of triethylamine gave quinazolines, pyrazolo[1,5-c]quinazoline and spiro quinazoline dimmers. The latter compounds are being reported for the first time. In addition, a 4,4-disubstituted quinazoline derivative is prepared and its X-ray crystal structure is reported.
The reaction of hydrazones of 2-aminoacetophenone with triphosgene in dichloromethane or benzene in the presence of triethylamine gave quinazolines, pyrazolo[1,5-c]quinazoline and spiro…
Essential oils (EOs) from the stems and leaves of Origanum vulgare L. grown in Saudi Arabia and Jordan were analyzed by gas chromatography–mass spectrometry (GC–MS) and GC–flame ionization…