Case study questions and answers CLS 421
CASE STUDY QUESTIONS
Max Burnell, a single, 48-year-old long-distance runner previously in good health, presented to his primary physician for a yearly physical examination, during which a suspicious-looking mole was noticed on the back of his left arm, just proximal to the elbow. He reported that he has had that mole for several years, but the mole gotten larger over the past two years. Max reported that he has noticed itchining the area of this mole with bleeding upon scratching over the past few weeks.
Clinical Examination:
Head, neck, thorax, and abdominal exams were normal, with the exception of a hard, enlarged, non-tender mass felt in the left axillary region. In addition, a 1.6 x 2.8 cm mole was noted on the dorsal upper left arm
Q1. What is the most Probable diagnosis ?
} a. melanoma
} b. adenocarcinoma
c. melanocarcinoma
} d. sarcoma
Q2. what is falls about malignant neoplasm
} a.very rapid growth rate.
b. Capsulated
} c. metastasized
} d. undifferentiated
Q3. carcinoma is a cancer of
} a. neurons
} b. lymphatic tissue
} c. connective tissue
d. epithelial tissue
2.65-year-old female reports about 2 months of tiredness, difficulty concentrating, fatigue and gastrointestinal discomfort with some decrease in appetite and numbness and tingling sensation in her hands and feet.
Clinical examination
by clinical examination she was normal except for some pallor and smooth, thick, red tongue
lab finding
RBC count 4x106 /µL3
HCT 34 %
HB% 8.5mg /dl
MCV 105 fl
MCH 25 pg
MCHC 23 %
Q1. What is the most probable diagnoses from the clinical picture?
a. Iron deficiency anemia
b. Sickle cell anemia
c. Pernicious anemia
Q2. The high MCV indicatefor;
a.Microcytic RBC
b.Macrocytic RBC
c.Normocytic RBC
Q3.Pernicious cousd by :
a. Iron deficiency
b.vit b12 deficiency
c.folic acid deficiency
31 years old male came to emergency clinic suffering of sever diarrhea, coughing and chills.
He has history of blood transfusion 2 years ago
Physical examination show:
Low grade fever,Left hand skin rash,Lymph nodes swollen,blood analysis confirmd presence of HIV AB +
Q1) What is the probably diagnosis?
} Acquired immune deficiency syndrome
Q2.What is the etology of AIDS?
a. Human pabiloma viral infection
} b. Hiv viral infection
c. Cryptococcal meningitis
Q3) Any of the immune system cells may be infected with HIV virus?
a)CD8 T toxic lymphocyte
B) lymphocyte
c) CD4 T helper lymphocyte
Q4 How the HIV virus transmeted?
a) blood ,s
b)semen ,
c)vaginal fluid
d)all of the above
A 40-year-old previously healthy woman, a non-smoker, has had episodes of fever, non-productive cough, and dyspnea over the past 3 months. Her symptoms disappeared after a month's vacation, but reappeared when she returned home to take care of her canaries. On physical examination there are no abnormal findings
Q1 What is most likely diagnosis?
a) Emphazyma
b) Bronchial asthma
c) Lung cancer
d) Lung abscess
Q2.What is the bronchial asthma?
Is a condition characterized by reversible bronchospasm and chronic inflammation of respiratory passages.
Q3. What are the Factors causing bronchial hyperresponsiveness in bronchial asthma are:
A. Allergens, e.g. pollen, house-dust, mite
B. Drugs : NSAIDs, aspirin
C. Viral infections of the respiratory tract
D. All of the above
A 51-year-old woman presented with weight loss (despite good appetite), palpitations, tremor, and heat intolerance.
On examination, she had diffusely enlarged thyroid, periorbital edema, and proptosis, as well as mild thickening of the skin in the pretibial area.
The lab results of thyroid-function tests:
(TSH) thyroid-stimulating hormone level :0.1 mU /ml < (normal range, 0.5 to 5.15)
(T3) triiodothyronine level: 557 ng/dl normal range, 100 to 190 ng /dl
(T4 )thyroxine level 17.9 μg /dl (normal range, 4.4 to 12.5 μg/dl)
Anti-TSH receptor antibodies 69.6 % . (normal range (0.0 to 16.0 Unit: %)
Q1: What is the diagnosis ?
Hyperthyroidism
Q2 What is the cause of hyperthyroidism, and why ?
Graves disease
because the patient has Anti-TSH receptor antibodies