Simple and Convenient Procedure for the Synthesis of 2-(3-(tert-Butoxycarbonylamino)propyl)-5-methylthiophenes
Balakit, Asim A. . 2013
2-(3-(tert-Butoxycarbonylamino)propyl)-5-methylthiophene and its 4-deuterio derivative have been synthesized by a simple and convenient method in a six step sequence from 2-methylthiophene. The final step involved bromine-lithium exchange on 4-bromo-2-(3-(tert-butoxycarbonylamino)propyl)-5-methylthiophene at low temperature in anhydrous tetrahydrofuran followed by treatment with water or D2O.
رقم الانشاء
52
مجلة/صحيفة
Iraqi National Journal of Chemistry
الصفحات
466-476
مزيد من المنشورات
