Department : Clinical Laboratory Sciences Course Number : CLS 415 Course Title : Virology Credit Hours : 2 + 0 = 2

• المقرر الدراسي: 415 كلن علم الفيروسات

Department              :           Clinical Laboratory Sciences

Course Number      :           CLS 415

Course Title             :           Virology

Credit Hours            :           2 + 0 = 2

 

 

Course Description:

This course deals with virus structures, morphology and classification. It also covers the physical, biochemical, and biological characters of viruses which include: virus-cell relationship (virus replication cycle), virus-host relationship (virus pathogenesis) and virus immunity. A general outline for laboratory isolation and identification of viruses in clinical specimens will  be presented. The clinical presentation of some virus diseases, their pathogenesis, laboratory diagnosis, prevention and controls will also be discussed.   

 

CLS 415:   Lectures Outline

 

Weeks                                               Subjects 

 

1.                                 Introduction: history and terminology

 

2.                                 Virus characters - physical and biochemical

 

3.                                 Basis of virus classification

 

4.                                 Virus replication cycle (virus-cell relationship)

 

5.                                 Virus pathogenesis and virus immunity

 

6.                                 Laboratory identification of viruses in clinical specimens:

                                 Direct diagnosis based on isolation, morphological and     

                                 biochemical characters

 

7.                                 Laboratory diagnosis of viruses in clinical specimens:

                                 Serological identification, Molecular diagnosis based on

                                 identification of virus nucleic acid, using DNA probe, DNA

                                 fingerprint and PCR

 

8.                                 Hepatitis viruses (HAV, HEV, HDV and TTV)

                                 Characters, epidemiology, pathogenesis and laboratory

                                 diagnosis

 

9.                               Hepatitis viruses (HBV & HCV) - Characters,  

                                 epidemiology, pathogenesis and laboratory diagnosis

 

10.                             Human Immunodeficiency Virus (HIV): types,

                                 characteristics, pathogenesis, epidemiology and

                                 laboratory diagnosis             

 

 

11.                             Herpes viruses: types, characteristics, importance and

                                 laboratory diagnosis

 

12.                             Encephalitis viruses: characteristics, pathogenesis and

                                 laboratory diagnosis

 

13.                             Meningitis viruses: characteristics, pathogenesis and

                                 laboratory diagnosis

 

14.                               Viral vaccines and anti-virus resistance

 

 

 

Assessments:

 

First Mid Term Examination:                       30

Second Mid Term Examination:                  30

Final Examination:                                        40

 

 

References:

 

Louis S. Kucera and Quentin N. Myrvik, Fundamentals of Medical Virology for Students of Medicine and Related Sciences, Publisher Lea Fabiger – Latest Edition