المنشورات و المؤلفات
Recently, nanoscale (<100 nm) inorganic materials, especially spherical shaped zinc oxide quantum dots
(ZnO-QDs), have received a lot of attention from the broad community because of their potential
utilization in various technologies. Due to...
Quercetol is a polyphenolic molecule present in vegetables and fruits, and is beneficial to human and animal health. The current work aimed to test cytotoxic and apoptotic effects of quercetol on HepG2 cells. Quercetol was isolated from Ocimum...
Molecular imaging is a novel technology used to study cellular and molecular mechanisms. MicroRNAs (miRNAs or miRs) play important roles in clinical diseases. Bioimaging of miRNA is a powerful tool used to study various biological phenomena....
tFor adequate cancer therapy, newer imaging modalities with more specific ligands for unique targetsare crucial. Underglycosylated mucin-1 (uMUC-1) antigen is an early marker of tumor development andis widely overexpressed on most tumors. A...
Envisaging the role of Co in theranautics and biomedicine it is immensely important to evaluate its antimicrobial
activity. Hence in this study CoO thin nanosheets (CoO-TNs) were synthesized using wet chemical solution
method at a very low refluxing...
A dual fluorophore-based color-tunable molecular beacon visualized
the microRNA-294 expression-dependent color change in cells.
Objectives A special vector system was developed to
monitor the in vitro and in vivo endogenous level of a
primary transcript of miR124a during neuronal
differentiation
Results The upstream regions of miR124a were
fused with luciferase (Gluc) and...
MicroRNAs (miRNAs or miRs) are implicated in several biological processes such as proliferation, differentiation, apoptosis, development and disease. A number of miRNA imaging tools have been developed due to the scientific and clinical...
Studying gene expression profile in a single cancer cell is important because
multiple genes are associated with cancer development. Quantum dots (QDs) have been
utilized as biological probes for imaging and detection. QDs display specific optical...
Salmon sperm DNA was used as a blocking agent to reduce background
fluorescence signals from gelatin-coated cell culture dishes.
Fluorescence monitoring of endogenous microRNA (miRNA or miR) activity
related to neuronal development using nano-sized materials provides crucial information
on miRNA expression patterns in a noninvasive manner. In this study, we report a new...
Evaluation of the function of microRNAs (miRNAs or miRs) through miRNA expression profiles during
neuronal differentiation plays a critical role not only in identifying unique miRNAs relevant to cellular
development but also in understanding...
A soft chemical solution process was used in synthesis of photocatalytic zinc oxide nanoparticles (ZnO- PNPs)at low temperature. The synthesized PNPs were characterized interms of their crystallinity, morphological, catalytic, spectroscopic and...
The wide scale use of copper oxide nanoparticles (CuONPs) due to their unique properties and important applications in magnetic,
thermal, electrical, sensor devices, and cosmetics makes human beings more prone to the exposure of CuONPs and its...
Abstract: Titanium dioxide (TiO2) nanoparticles are among the top five nanoparticles used in consumer products, paints, and pharmaceutical preparations. Given that exposure to such nanoparticles is mainly via the skin and inhalation, the present...
Arsenic trioxide-mediated oxidative stress and genotoxicity in human hepatocellular carcinoma cells.
Background: Arsenic is a ubiquitous environmental toxicant, and abnormalities of the skin, lung, kidney, and liver are the most common outcomes of long-term arsenic exposure. This study was designed to investigate the possible mechanisms of...
The Hepatitis B virus (HBV) is a mostly double-stranded DNA virus in the
Hepadnaviridae family. HBV is a common viral pathogen that causes a substantial
health burden worldwide. Significant progress has been made in the past few decades
in...
Multimodal imaging systems may eliminate the disadvantages of individual imaging modality by
providing complementary information about cellular and molecular activites. In this sutdy, we developed
a reverse complementary multimodal imaging system to...
The domestication of livestock represented a crucial step in human history. By using endogenous
retroviruses as genetic markers, we found that sheep differentiated on the basis of their “retrotype”
and morphological traits dispersed across Eurasia...
MicroRNAs (miRNAs), a class of small non-coding RNAs, have been reported to be functionally
involved with cellular metabolism and a variety of diseases. The importance of miRNA expression and functional
targeting has recently become a focus of...
Dual optical microRNA (miRNA) imaging systems, bioluminescent reporter gene (a signal-off mechanism)-
or fluorescent molecular beacon (MB) (a signal-on mechanism)-based miRNA imaging system, have individually
allowed us to sense miRNA biogenesis in...