المنشورات و المؤلفات
Purpose: Monitoring of amphotericin-B (AmB) in Saudi critically ill patients in ICU after IV administration of 0.5-0.75 mg/kg/day AmB as Fungizone. Developing a fast, robust, selective, sensitive, and precise UPLC MS/MS method, to study the...
Amphotericin B (AmB) is the first-line agent for the treatment of life-threatening invasive fungal infections. The aim of this study was to monitor AmB in critically ill Saudi patients in ICU after i.v. administration of 0.68 ± 0.1 mg/kg/day...
Enhancement of Dissolution and Bioavailability of Piroxicam Via Solid Dispersions with Phospholipids
Résumé / Abstract
Two modified cyclodextrins, heptakis-(2,6-di-O-methyl)-β-Cyclodextrin (DM-β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD), were adopted for preparing piroxicam-cyclodextrin (PIR-CD) inclusion complexes, in comparison to '3-...
This investigation describes a new precise, sensitive and accurate stereoselective HPLC method for the simultaneous determination of donepezil enantiomers in tablets and plasma with enough sensitivity to follow its pharmacokinetics in rats up to 12...
Polyethylcyanoacrylate (PECA) nanoparticles (NPs) have been employed as biodegradable polymeric carriers for oral (PO) delivery of ketorolac. The nanoparticles were prepared by polymerization technique at room temperature in a continuous aqueous...