Associate Professor | Faculty of Applied Medical Sciences

Address: Department of Community Health Sciences College of Applied Medical Sciences King Saud University P.O.Box 10219, Riyadh, 11433, Saudi Arabia.

CV

Dr. CHANDRAMOHAN GOVINDASAMY
Associate Professor
Department of Community Health Sciences
College of Applied Medical Sciences
King Saud University
P.O.Box 10219, Riyadh, 11433
Saudi Arabia.
Phone: +9664697434
Mobile: +966508393530
Email: gcmohanphd@yahoo.com
 
PROFESSIONAL EXPERIENCE
 
2017- Present :  Associate Professor
                             Department of Community Health Sciences,
                             College of Applied Medical Sciences, King Saud University,
                             Riyadh, Saudi Arabia
 
2012- 2017     :   Assistant Professor
                             Department of Community Health Sciences,
                             College of Applied Medical Sciences, King Saud University,
                             Riyadh, Saudi Arabia
 
2009- 2012    :   Post Doctoral Researcher
                            Department of Community Health Sciences,
                            College of Applied Medical Sciences, King Saud University,
                            Riyadh, Saudi Arabia
 
2008- 2009    :   Post Doctoral Researcher
                            Department of Food and Nutrition Sciences,
                            College of Food and Agricultural Sciences, King Saud University,
                            Riyadh, Saudi Arabia
AWARDS AND HONOURS RECEIVED

  • Special Recognition and Special Appreciation Award received as Organizing Committee Member for the “3rd International Conference on Clinical & Experimental Cardiology” was held in Chicago, USA (2013).
  • Senior Research Fellowship awarded by Indian Council of Medical Research, New Delhi, India (2005-2007).        
  • University Research Fellowship awarded by Annamalai University, Tamilnadu, India (2004-2005).

PRIZES

  • First prize awarded for best oral presentation in the UGC-Sponsored “National Conference on Natural Products in Health” was held at Annamalai University, Tamil Nadu, India (2005).

 EDUCATION
 
2004-2008      :   Ph.D. in Biochemistry (Graduated on April 2008)
                            Annamalai University, Tamilnadu, India
(Thesis Title: Isolation and characterization of active principle from Casearia esculenta (Roxb.) root and its effect on glycaemic control in normal and streptozotocin-induced diabetic rats)
 
2002-2004      :   Master of Philosophy in Biochemistry (Graduated on January 2004)
                             Annamalai University, Tamilnadu, India
(Thesis Title: Antimicrobial activity of certain plant extracts and synthetic compounds)
 
2000-2002      :   Master of Science in Biochemistry (Graduated on May 2002)
                            Annamalai University, Tamilnadu, India
 
1997-2000      :   Bachelor of Science in Biochemistry (Graduated on May 2000)
                            University of Madras, Tamilnadu, India.
 
RESEARCH EXPERIENCE
2002-Current :   15 years research experiences in the field of Biochemistry.
MAJOR FIELD OF SPECIALIZATION

  • Pharmacology, Toxicology, Molecular Biology and Phytochemistry.

CURRENT AREA OF RESEARCH

  • Nutrition and Natural Products in Cardiac Diseases and Diabetes Mellitus.

MEMBERSHIP IN SOCIETY
 

  • World Public Health Nutrition Association (WPHNA)
  • Society for Free Radical Research (SFRR), India
  • Indian Science Congress, India Society for Biological Chemist (SBC), India
  • Biochemical Society (BCS), India
  • Member of Indian Society for Atherosclerosis Research (ISAR)
  • Member of International Biographical Association (IBA)

PATENT

  1. G. Chandramohan, K.V. Pugalendi, S. Ignacimuthu. A novel compound 3-hydroxymethyl xylitol and process for preparing the compound having antidiabetic activity. Patent Number: 243139, India.

PUBLICATIONS

  1. Dharman Govindaraj, Chandramohan Govindasamy and Mariappan Rajan. Binary Functional Porous Multi Mineral–Substituted Apatite Nanoparticles for Reducing Osteosarcoma Colonization and Enhancing Osteoblast Cell Proliferation (2017).  Materials Science and Engineering: C, 79, 875–885.
  2. Chandramohan Govindasamy. Kaempferol, a flavonoid, ameliorates hyperglycemia by attenuating the key enzymes of carbohydrate metabolism in streptozotocin–induced experimental diabetic rats (2017). Progress in Nutrition (Accepted).
  3. Amal A. Aloud, Chinnadurai Veeramani,  Chandramohan Govindasamy,  Mohammed A. Alsaif, Ahmed S. El Newehy, Khalid S. Al-Numair.  Galangin, a dietary flavonoid, improves antioxidant status and reduces hyperglycemia-mediated oxidative stress in streptozotocin-induced diabetic rats. (2016). Redox Report Dec 28:1-11. doi: 10.1080/13510002.2016.1273437.
  4. Khalid S. Al-Numair, Chinnadurai Veeramani, Mohammed A. Alsaif, and Govindasamy Chandramohan (2015). Influence of kaempferol, a flavonoid compound, on membrane-bound ATPases in streptozotocin-induced diabetic rats. Pharmaceutical Biology, 53(9):1372-8.
  5. Al-Numair  KS, Chandramohan G, Veeramani C, Alsaif MA (2015). Ameliorative effect of kaempferol, a flavonoid, on oxidative stress in streptozotocin-induced diabetic rats. Redox Report 20(5):198-209.
  6. Govindasamy Chandramohan, Khalid S. Al-Numair, Mohammed A. Alsaif and Chinnadurai Veeramani (2015). Antidiabetic effect of kaempferol a flavonoid compound, on streptozotocin-induced diabetic rats with special reference to glycoprotein components. Progress in Nutrition 17 (1), 50–57.
  7. Govindasamy Chandramohan, K.S Al-Numair, C. Veeramani, M. A. Alsaif, A. Madi Almajwal (2015). Protective effect of kaempferol, a flavonoid compound, on oxidative mitochondrial damage in streptozotocin-induced diabetic rats. Progress in Nutrition 17; 3 238-244.
  8. Veeramani C, Al-Numair KS, Chandramohan G, Alsaif MA, Pugalendi KV (2015). Influence of Cardiospermum halicacabum leaf extract on membrane bound ATPases in streptozotocin-induced diabetic rats. Afr J Tradit Complement Altern Med. 12(3):68-74.
  9. Veeramani C, Al-Numair KS, G. Chandramohan, M.A. Alsaif and K.V.  Pugalendi (2015).  Effect of ethyl acetate fraction of Melothria maderaspatana leaf on membrane bound ATPases in DOCA–salt induced hypertensive rats. Progress in Nutrition 17, 331-338.
  10. Khalid S. Al-Numair, Govindasamy Chandramohan, Mohammed A. Alsaif, Chinnadurai Veeramani and Ahmed S. El Newehy (2014). Morin, a flavonoid, on lipid peroxidation and antioxidant status in experimental myocardial ischemic rats. The African Journal of Traditional, Complementary and Alternative medicines, 11(3):14-20.
  11. Khalid S. Al-Numair, Chinnadurai Veeramani, Mohammed A. Alsaif and Govindasamy Chandramohan (2014).  Efficacy of morin on serum and heart tissue lipids in rats subjected to isoproterenol-induced myocardial injury. Progress in Nutrition, 16 (1); 16-24.
  12. Veeramani C, Al-Numair  KS, Chandramohan G, Alsaif MA, Pugalendi KV (2014). Renal protective effect ofMelothria maderaspatana leaf fraction on uninephrectomized deoxycorticosterone acetate–salt hypertensive rats. Progress in Nutrition 16: 204-211.
  13. Khalid S. Al-Numair, Chinnadurai Veeramani, Mohammed A. Alsaif and Govindasamy Chandramohan (2013). Influence of kaempferol on lipid metabolic changes in streptozotocin induced diabetic rats. Progress in Nutrition, 15 (4); 255-264.
  14. Khalid S. Al-Numair, Govindasamy Chandramohan, Chinnadurai Veeramani and Mohammed A. Alsaif (2012). Morin, a flavonoid, prevents lysosomal damage in experimental myocardial ischemic rats. Journal of Medicinal Plants Research 6(18); 3445-3449.
  15. Chinnadurai Veeramani, Khalid S. Al-Numair, Govindasamy Chandramohan, Mohammed A Alsaif, Kodukkur Viswanathan Pugalendi (2012). Protective effect of Cardiospermum halicacabum leaf extract on glycoprotein components on STZ-induced hyperglycemic rats. Asian Pacific Journal of Tropical Medicine 5(12):939-44.
  16. Chinnadurai Veeramani, Khalid S. Al-Numair, Govindasamy Chandramohan, Mohammed A Alsaif, Kodukkur Viswanathan Pugalendi (2012). Antihyperlipidemic effect of Melothria maderaspatana leaf extracts on DOCA-salt induced hypertensive rats. Asian Pacific Journal of Tropical Medicine, 5(6)434-439.
  17. Khalid S. Al-Numair, Govindasamy Chandramohan, Mohammed A. Alsaif, Arul Albert Baskar (2012). Protective effect of morin on cardiac mitochondrial function during isoproterenol induced myocardial infarction in male Wistar rats. Redox Report 17(1): 14-21.
  18. Chinnadurai Veeramani, Khalid S. Al-Numair, Govindasamy Chandramohan, Mohammed A. Alsaif and Kodukkur Viswanathan Pugalendi (2012). Protective effect of Melothria maderaspatana leaf fraction on electrolytes, catecholamines, endothelial nitric oxide synthase and endothelin-1 peptide in uninephrectomized deoxycorticosterone acetate–salt hypertensive rats. Journal of Natural Medicines 66; 535-543.
  19. Chinnadurai Veeramani, Khalid S. Al-Numair, Govindasamy Chandramohan, Mohammed A. Alsaif and Kodukkur Viswanathan Pugalendi (2012). Antihypertensive effect of Melothria maderaspatana leaf fractions on DOCA-salt-induced hypertensive rats and identification of compounds by GC–MS analysis. Journal of Natural Medicines 66; 302-310.
  20. Khalid S. Al-Numair, Govindasamy Chandramohan, Mohammed A. Alsaif. (2012). Pretreatment with morin, a flavonoid, ameliorates adenosine triphosphatases and glycoproteins in isoproterenol induced myocardial infarction in rats. Journal of Natural Medicines 66:95–101.
  21. Khalid S. Al-Numair, Govindasamy Chandramohan and Mohammed A. Alsaif  (2011). Influence of camel milk on glycoprotein Components in streptozotocin diabetic rats. Journal of Camel Practice and Research 18 (1); 1-6.
  22. Govindasamy Chandramohan, Khalid S. Al-Numair, Kodukkur Viswanathan Pugalendi. (2011). Influence of 3-hydroxymethyl xylitol, a novel antidiabetic compound isolated from Casearia esculenta (roxb.) root, on glycoprotein components in streptozotocin-diabetic rats. Journal of Asian Natural Product Research 13 (8); 700-706.
  23. Khalid S. Al-Numair, Govindasamy Chandramohan and Mohammed A. Alsaif (2011). Effect of camel milk on collagen abnormalities in streptozotocin-diabetic rats. African Journal of Pharmacy and Pharmacology Vol. 5(2), pp. 238 – 243.
  24. Khalid S. Al-Numair, Mohammed A. Alsaif, Kimberly Barber-Heidal and Chandramohan  Govindasamy (2011). Effects of Omega-3 and Omega-6 fatty acids on lipids panel in Riyadh City, Saudi Arabia. Asia Life Sciences 20(2): 431-443.
  25. Khalid S.Al-Numair, Govindasamy Chandramohan, Mohammed A. Alsaif and Govindasamy Sundaraselvan (2011). Antihyperglycemic effect of camel milk in streptozotocin-diabetic rats, Asian Life Sciences, 20(1): 1-11.
  26. Balasubramanian Sudhakar, Panneerselvam Kalaiarasi, Khalid S. Al-Numair, Govindasamy Chandramohan, Rama K. Rao, Kodukkur V. Pugalendi (2011). Effect of combination of edible oils on blood pressure, lipid profile, lipid peroxidative markers, antioxidant status, and electrolytes in patients with hypertension on nifedipine treatment. Saudi Medical Journal 32 (4):179-185.
  27. Govindasamy Chandramohan, Khalid S. Al-Numair, Muruhan Sridevi and Kodukkur Viswanathan Pugalendi (2010). Antihyperlipidemic activity of 3-hydroxymethyl xylitol, a novel antidiabetic compound isolated from Casearia esculenta (Roxb.) root, in streptozotocin-diabetic rats. Journal of Biochemical and Molecular Toxicology, 24 (2), 95 – 101.
  28. Khalid S. Al-Numair, Govindasamy Chandramohan and Mohammed A Alsaif (2010). Antioxidants role of camel milk in streptozotocin-diabetic rats. Journal of Camel Practice and Research, 17 (2), 1-8.
  29. Khalid S. Al-Numair, Govindasamy Chandramohan, Mohammed A. Alsaif, Narasimhanaidu Kamalakannan and Govindasamy Sundaraselvan (2010). Effect of camel milk on the activities of ATPases in normal and streptozotocin-diabetic rats. Polish Journal of Food and Nutrition Sciences.60, 4,377-382.
  30. Govindasamy Chandramohan, Khalid S. Al-Numair, Kodukkur Viswanathan Pugalendi. (2009). Restoration of altered plasma, erythrocyte and liver antioxidant levels by 3-hydroxymethyl xylitol in streptozotocin-diabetic rats. International Journal of Integrative Biology. 5; 3, 176.
  31. Govindasamy Chandramohan, Khalid S. Al-Numair and Kodukkur Viswanathan  Pugalendi (2009). Effect of 3-hydroxymethyl xylitol on hepatic and renal functional markers and protein levels in streptozotocin-diabetic rats. African Journal of Biochemistry Research 3(4); 198-204.
  32. G. Chandramohan, Savarimuthu Ignacimuthu, and K.V.Pugalendi. (2008). A novel compound from Casearia esculenta (Roxb.) root and its effect on carbohydrate metabolism in streptozotocin - diabetic rats. European Journal of Pharmacology, 590: 437–443.
  33. S. Senthil, G.Chandramohan and K.V. Pugalendi. (2006). Isomers (oleanolic and ursolic acids) differ in their protective effect against isoproterenol-induced myocardial ischemia in rats. International Journal of Cardiology: 119,131-133.
  34. M. Sridevi, G. Chandramohan and K.V.Pugalendi. (2007). Protective effect of Solanum surattense leaf-extract on blood glucose, oxidative stress and hepatic marker enzymes in STZ - diabetic rats. Asian Journal of Biochemistry 2 (4): 247- 255.
  35. G. Chandramohan, A.Manimekalai, C.Anandi, K.V.Pugalendi (2005). Studies on the antimicrobial activity of N-salicyloyi 1-2-6-diphenylpiperidin-4-one hydrazone and its methyl derivative. Indian Journal of Applied Microbiology: 7-11.
  36. G. Chandramohan, N. Rajendra Prasad, C. Anandi, K.V. Pugalendi. (2005). Antimicrobial activity of two south Indian medicinal plants. Journal of the Annamalai University, Part-B, Science. 65-71. 

PAPERS PRESENTED in INTERNATIONAL CONFERENCE/SEMINAR

  1. ISER- 191st International Conference on Science, Health and Medicine (ICSHM) on 6th-7th July, 2017 at Tokyo, Japan presented paper entitled “Protective effects of morin on altered plasma lipid peroxidation and nonenzymic antioxidants in isoproterenol-induced myocardial infarcted rats".
  2. 7th Asia-Pacific Biotech Congress was held during July 13-15,2015 at Beijing, China presented paper entitled “ The bioflavonoid kaempferol attenuates circulatory lipids in experimental diabetic rats” (Oral Presentation).
  3. Australian & New Zealand Obesity Society 2014 Annual Scientific Meeting on 16th - 18th October 2014, New South Wales, Sydney, Australia presented paper entitled “Ameliorative effect of kaempferol a flavonoid against streptozotocin generated oxidative stress induced diabetic rats” (Oral Presentation).
  4. Australian & New Zealand Obesity Society 2014 Annual Scientific Meeting on 16th - 18th October 2014, New South Wales, Sydney, Australia presented paper entitled “Effect of camel milk on plasma glucose concentration and lipid profile in streptozotocin induced diabetic rats: Camel milk may better therapeutic potential for obese diabetic patients” (Poster Presentation).
  5. 5th International Conference on Biomarkers and Clinical Research, on  April 15-17th, 2014, University of Oxford, United Kingdom delivered a lecture on “Protective effect of morin on cardiac mitochondrial function during isoproterenol induced myocardial infarction in male Wistar rats” (Invited Talk).
  6. Participated the congress entitled “9th Annual Biomarkers Congress 2014” Manchester, United Kingdom on 25–26 February 2014 (Participated).
  7. 15th European Conference on the Spectroscopy of Biological Molecules (ECSBM) on 25–30, August 2013, at University of Oxford, England, United Kingdom presented paper entitled “Isolation and identification of a novel anti-diabetic compound of 3-hydroxymethyl xylitol (3-HMX) from Casearia Esculenta (Roxb.) root, on key carbohydrate metabolic enzymes, lipid peroxides and antioxidants in streptozotocin-induced diabetic rats” (Oral Presentation).
  8. World Congress on Endocrinology on August 26-28, 2013 at North Carolina, USA delivered a lecture on “Camel milk contains insulin like protein on attenuating the key enzymes activities of carbohydrate metabolism in Streptozotocin-induced diabetic rats” (Invited Talk).
  9. 3rd International Conference on Clinical & Experimental Cardiology, on 15-17th April, 2013, Chicago, USA delivered a lecture on “Pretreatment with Morin, a flavonoid, ameliorates adenosine triphosphatases and glycoproteins in isoproterenol induced myocardial infarction in rats” (Invited Talk).
  10. “World Nutrition Rio 2012” on 27-30th April 2012, Rio De Janeiro, Brazil, presented paper entitled “Protective effect of Melothria Maderaspatana leaf fraction on electrolytes, catecholamines, endothelial nitric oxide synthase (enos) and endothelin-1 (et-1) peptide on uninephrectomized doca-salt hypertensive rats” (Oral Presentation).
  11. “Experimental Biology 2012” on April 21-25th, 2012, San Diego, California, USA presented paper entitled “Pretreatment with morin ameliorates lipid profiles in isoproterenol-induced myocardial infarction in wistar rats”. (Oral Presentation).
  12. “2nd World Congress on Diabetes & Metabolism” on 6-8th December 2011, Philadelphia, Pennsylvania, USA delivered a lecture on “Influence of 3-hydroxymethyl xylitol, a novel antidiabetic compound isolated from Casearia esculenta (roxb.) root, on glycoprotein components in streptozotocin-diabetic rats”(Invited Talk).
  13. Participated the symposium entitled “The Use of Zinc Finger Nucleases for the Development of Next Generation Cell Lines and Animal Models” Heidelberg, Germany” on 5th December 2011.
    (Participated).
  14. “Experimental Biology 2011” on 9-13th April, 2011, Washington, USA, presented paper entitled “Effects of Omega-3 and Omega-6 fatty acids on lipids panel in Riyadh City, Saudi Arabia” (Oral Presentation).
  15. “International Conference on Diabetes & Metabolism” on 13-14th December 2010, Santa Clara, California, USA, delivered a lecture on “Antihyperlipidemic Activity of 3-Hydroxymethyl Xylitol, a Novel Antidiabetic Compound Isolated from Casearia esculenta (Roxb.) Root, in Streptozotocin-Diabetic Rats”. (Invited Talk).
  16. International Conference on Natural Products in Health and ISARCON-2008 held during 8-10th December, 2008, in the Department of Biochemistry and Biotechnology, Annamalai University, Chidambaram, Tamilnadu. INDIA, a paper presented “A novel compound from Casearia esculenta (Roxb.) root and its effect on carbohydrate metabolism in streptozotocin - diabetic rats”. (Invited Talk).

PAPERS PRESENTED AND PARTICIPATED IN NATIONAL / SEMINARS, SYMPOSIA, CONFERENCES
 

  1. IIIrd National Conference on Natural Products, Free Radicals and antioxidants in Health, Annamalai University, Annamalainagar, India (Mar 2007).
  2. UGC-Sponsored National Conference on Natural Products in Health, 26-27th Feb. 2005 held at Annamalai University, Tamil Nadu, and India, a paper presented “A novel compound from Casearia esculenta (Roxb.) root and its effect on carbohydrate metabolism in streptozotocin - diabetic rats” (First prize awarded for best oral presentation).
  3. 3rd State level seminar on Phytochemistry, Theivanai Ammal College for women, Villupuram, 25th Sep, 2004. Tamil Nadu, India, a paper presented “Antimicrobial activity of certain plant extracts and synthetic compounds”. (Oral Presentation).

CONFRENCE ORAGANIZED

  • Worked as an organizing committee member for the 3rd International Conference on Clinical & Experimental Cardiology, Chicago, USA (2013).
  • Worked as an organizing committee member for the 2nd World Congress on Diabetes & Metabolism, Philadelphia, USA (2011).
  • International conference and Expo on Cardiology and Cardiac Surgery April 04-06, 2016, Dubai, UAE.

 
CONFERENCE/TRAINING/WORKSHOP ATTENDED
 

  • The Clinical Research and Data Management Course, April 29-30th, 2013, King Saud University, Riyadh, Saudi Arabia.
  • 94th Indian Science Congress Association, Annamalai University, Annamalainagar, India (Jan, 2007).
  • Society for Free Radical Research- Satellite Meeting, All India Institute of Medical Science, New Delhi, India (Feb 11-12, 2008).
  • National conference on “Recent trends in Biochemistry/Biotechnology with special reference to natural products in health” Annamalai University, Annamalainagar, India (Feb 2006).
  • IVth SERC School in Chronobiology held at Annamalai University, Annamalainagar, India (Jan 2006)
  • International conference on natural products, free radicals and radioprotectors in health (NFRH-2004), III- Annual meeting of SFRR-India.
  • XIV “Annual Scientific Meet of Society of Biological Chemists” (India), Annamalaingar, February 2004.
  • XIII “Annual Scientific Meet of Society of Biological Chemists” (India), Annamalainagar Chapter, February 2003.
  • XII “Annual Scientific Meet of Society of Biological Chemists” (India), Annamalainagar Chapter, February 2002.
  • Centre for Bioseparation Technology, A Short term hands on Training course “Monolithic Chromatoghraphic Systems” 31st January & 1st February 2005, Vellore Institute of Technology, Vellore, India.
  • UGC Sponsored National Workshop On “Herbal drug standardization” 19th & 20th February, 2005. Department of Pharmacy, Annamalai University, Chidambaram, Tamil Nadu, India.

 REVIEWER IN PEER REVIEWED JOURNALS

  • Redox Report
  • Food and Chemical Toxicology
  • Biochimi
  • Basic & Clinical Pharmacology & Toxicology
  • Journal of Cell and Animal Biology
  • Journal of Food Biochemistry
  • Journal of Agricultural Biotechnology and Sustainable Development
  • Journal of African Studies and Development
  • Asian Journal of Pharmaceutical and Biological Research
  • Journal of Basic and Clinical Pharmacy

EDITORIAL MEMBER

  • Research in Pharmaceutical Biotechnology
  • Journal of Research in Biochemistry
  • Pharmacognosy Research
  • Journal of Research in Biology.
  • Quarterly Journal of Surgical Sciences

MEMBER IN THE BOARD OF EXAMINERS

  • To adjudicate the thesis submitted for the award of Degree of Doctor of Philosophy (Ph.D.) to Bharathiar University, Coimbatore and Bharathidasan University, Tamilnadu, India.

AS A SESSION CHAIR PERSON

  • For the track 5 of “Advanced Technologies for Treatment of Diabetes” in the 2nd World Congress on Diabetes & Metabolism” on 6-8th December 2011, at Philadelphia, Pennsylvania, USA.

COMPUTING SKILLS

  • Scientific software:  Familiarized with software’s related to DNA and protein sequence analysis BLAST, CLUSTAL, BIOEDIT, MEGA  and genetic relationship analysis software like Bio-Gene Software (Vilber  Loumert, France). I have been using number of online programs routinely for homology searches, sequence alignment and for other research.
  • Applications: Microsoft Office Suite, Origin, Chemdraw, Sigma Plot

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