Dina M. Metwally*, Razan A. Al-Talhi, Ibrahim A.H. Barakat, Manal F. ElKhadragy. (2019). Effects of Eugenol on Haemoproteus columbae in domestic pigeons (Columba livia domestica) from Riyadh, Saudi Arabia
Metwally, Dina M. . 2019
Eugenol was investigated for the treatment of Haemoproteus columbae (H. columbae)-infected squabs (young domestic pigeons, Columba domestica). Thirty naturally-infected squabs were divided into three groups of ten each. One group was treated with eugenol, while the positive and negative control groups were administered buparvaquone (Butalex®) and distilled water, respectively. The number of infected red blood cells was calculated in all groups before and after treatment at 4-d intervals for 16 d. The results showed a significant therapeutic effect of eugenol, with a progressive decrease in the number of infected red blood cells from 89.20 ± 2.11 before treatment to 0.90 ± 0.31 at the end of treatment (P ≤ 0.05). Butalex® was able to suppress the number of infected red blood cells from 93.70 ± 1.72 before treatment to 0.90 ± 0.35 at the end of the experiment (P ≤ 0.05). Eugenol showed therapeutic effects against H. columbae and may be regarded as a candidate for further studies to develop new drugs against blood parasites, in both animals and humans.
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