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Dr. rer. nat Elsayed Ahmed Elsayed

Associate Professor

Faculty Staff Member

كلية العلوم
Building 5, AB107
المنشورات
مقال فى مجلة
2017

Optimization of Cordycepin Extraction from Cordyceps militaris Fermentation Broth

El-Enshasy, M Soltani, R Abd Malek, I Ware, Ramli, E A Elsayed, R Aziz, and H A . 2017

Cordyceps is one of the components of traditional Chinese medicine. This mushroom becomes worldwide famous due to its significant therapeutic effects on various diseases. Nucleoside like cordycepin, a major bioactive compound from Cordyceps militaris, is commonly known as promising anticancer and antitumor compound. The aim of study is to determine an optimal mixture ratio of solvent-solvent-based extraction method, which is used for extraction of cordycepin, from cultivated Cordyceps militaris DSMZ 23612 fermentation broth. Hence, the optimization process was performed using statistical (RSM) design leaded an optimal cordycepin extraction using solvent mixture including hot water (23%), ethanol (30%), methanol (25%) and ethyl acetate (22%). In addition, the final extracted cordycepin (786.94 mgL-1 of 81% purity) was achieved through extraction parameters as sample: solvent ratio (v/v), extraction temperature, extraction time and frequency at (1:10), 35 °C, 90 min and 1 cycle, respectively. The experimental values obtained were fit with those predicted, thus indicate the suitability of RSM and method for optimization of cordycepin extraction

نوع عمل المنشور
Research Article
رقم المجلد
76
رقم الانشاء
6
مجلة/صحيفة
Journal of Scientific & Industrial Research
الصفحات
355-361
مزيد من المنشورات
publications

Background: Pectinase enzymes present a high priced category of microbial enzymes with many potential applications in various food and oil industries and an estimated market share of $ 41.4…

بواسطة El Enshasy, Elsayed EA, Suhaimi N, MalekRA, Esawy M
2018
publications

A series of azocompounds containing methyl salicylate 4a–k and 1-naphthyl moiety 6–8 was synthesized and tested as anticancer
agents. Nitrosation of methyl 5-amino-2-hydroxybenzoate or 1-…

بواسطة El-Naggar M, El-Shorbagi A-N, El-Naggar D, Amr AE, Al-Omar M, Elsayed EA
2018
publications

Invertase (β-D-fructofuranoside fructohydrolase; EC 3.2.1.26) constitutes an improtant microbial enzyme with wide applications in differnt food and pharmaceutical sectors. The present work used…

بواسطة Elsayed EA, El Enshasy HA
2018