Protective Effect of Curcumin on γ-radiation Induced Chromosome Aberrations in Human Blood Lymphocytes. Saudi Journal of Biological Science
AlSuhaibani, Entissar Suliman . 2009
The present work is aimed at evaluating the radioprotective effect of curcumin on γ-radiation induced genetic toxicity. The DNA damage was analyzed by the frequencies of chromosome aberrations assay. Human lymphocytes were treated in vitro with 5.0 μg/ml of curcumin for 30 min at 37 °C then exposed to 1, 2 and 4 Gy gamma-radiation. The lymphocytes which were pre-treated with curcumin exhibited a significant decrease in the frequency of chromosome aberration at 1 and 2 Gy radiation-induced chromosome damage as compared with the irradiated cells which did not receive the curcumin pretreatment. Thus, pretreatment with curcumin gives protection to lymphocytes against γ-radiation induced chromosome aberration at certain doses.
Aphids are important agricultural pests worldwide. Their control is largely based on chemical insecticides. One species that shows important invasive abilities and hostplant- related differences…
Previously, a plant steroid, diosgenin, altered cell cycle distribution and induced apoptosis in human osteosarcoma
cell line. The study objective was to investigate if antiproliferative…
Capsaicin (8-methyl-N-vanillyl-6-nonenamide), possesses anti-proliferative properties that can be used as anticancer