المنشورات و المؤلفات

Aphids are important agricultural pests worldwide. Their control is largely based on chemical insecticides. One species that shows important invasive abilities and hostplant- related differences is Therioaphis trifolii (Monell) (Hemiptera: Aphididae...
Previously, a plant steroid, diosgenin, altered cell cycle distribution and induced apoptosis in human osteosarcoma cell line. The study objective was to investigate if antiproliferative effect of diosgenin was similar for human colon cancer (Caco-2...
Capsaicin (8-methyl-N-vanillyl-6-nonenamide), possesses anti-proliferative properties that can be used as anticancer intervention as promising cancer chemo-preventive constituent. We investigated capsaicin inhibitory activity against colon cancer (...
Garlic (allium sativum) possesses anti-proliferative properties that can be used in anticancer intervention as promising cancer chemo-preventive constituent. Diallyl disulfide (DADS) is an oil soluble sulfur organic compound. We investigated DADS...
Natural compounds have been used to treat cancer because of their low cytotoxicity and less adverse effects. Ginger has long been used in traditional medicine as it contains active phenolic compounds that have antioxidant, anti-cancer, anti-...
An understanding of the ABO and Rh blood group systems is important for blood transfusions and is also pertinent due to their potential association with certain morbidities and susceptibilities to infections. To investigate the diversity and...
Objective: To investigate the radioprotecting ability of the extract of the medicinal plant Holarrhena antidysentrica, especially to protect DNA from gamma- radiation induced damages. Materials and Methods: Hydo-alcoholic extract of dried roots of...
Objective: To investigate the molecular mechanism of anti tumor activity of Clerodendron infortunatum extract (CIE) under in vitro condition. Materials and Methods: The cytotoxic activity of CIE extract was tested on murine tumor cells (Dalton’s...
AIM OF STUDY: The present work aimed to examine the efficacy of two ayurvedic formulations, Brahma Rasayana (BRM) and Chyavanaprash (CHM) to alleviate doxorubicin (DOX) induced acute cardiotoxicity. MATERIALS AND METHODS: Swiss albino mice were...
In order to investigate the diversity of ABO and Rh blood group genes in the Saudi Arabian population, we assembled the phenotypic data of approximately 66,000 subjects from ten representative Saudi populations: Al-Khobar, Riyadh, Tabuk/Madina Al-...
Objective: To evaluate the anti tumor activity of Coscinium fenestratum extract under in vitro and in vivo conditions. Materials and Methods: The cytotoxic activity of C. fenestratum extract was tested on HeLa cells by MTT assay. The apoptosis-...
The aim of this study was to compare the characterization of prostate cancer using the conventional and 2005 ISUP modified Gleason systems. Materials and Methods: The study employed samples from 40 prostate cancer patients with resection, biopsy and...
Acetone (dimethyl ketone) and 2-propanone (CH3COCH3) is an organic chemical compound which belongs to ketones. Acetone is produced normally in human body, but its excessive levels has toxic hazard effects. Acetone is used in many fields, but...
Nanotechnology applications have occurred rapidly. Zinc oxide nanoparticles (ZnO NPs) have useful effects for their less hazards on the environment and for their application usages: paints, cosmetics, biomedicine and food as zinc supplements. ZnO...
It is increasingly clear that the three RAS genes, N-. H- and K-RAS, encode 21 kDa proteins which act as intracellular switches, play a signal transduction pathway in controlling cell growth and differentiation. The three genes are highly homologous...
Nickel nanoparticles (NiNPs) are increasingly used in various applications due to their unique properties. However, there is little information concerning the toxicity of NiNPs in the human skin cell (A431). The present study was designed to...
The objective of this investigation was to develop and evaluate potential radio-protective of Aspirin through assessment of structural chromosomal aberrations (CA) induced by γ-ray in Swiss Albino male mice. Aspirin at doses of 0.5, 5 and 50 mg/kg...
This study evaluated the effects of γ radiation on spermatozoa based on the morphological characteristics of sperm in the caudal epididymis of SWR/J mice. In this study, various abnormal sperm shapes (amorphous heads, hook-less, mid-piece defect,...
The present work is aimed at evaluating the radioprotective effect of curcumin on γ-radiation induced genetic toxicity. The DNA damage was analyzed by the frequencies of chromosome aberrations  assay. Human lymphocytes were treated in vitro with 5.0...
In the absence of permanent rivers or bodies of water, half of the Saudi Arabia domestic water consumption is provided through desalination. The other half is derived from groundwater. Groundwater from the Disi aquifer is already used for drinking...
The present work evaluates the radioprotective effect of curcumin on γ-radiation-induced genetic toxicity. The DNA damage was analysed by the frequencies of Sister Chromatid Exchanges (SCEs). Human lymphocytes were treated in vitro with 5.0 μg/ml of...
Aspartame (a-Laspartyl-L-phenylalanine 1-methylester) is a dipeptide low-calorie artificial sweetener that is widely used as anonnutritive sweetener in foods and drinks. The safety of aspartame and its metabolic breakdown products (phenylalanine, ...