Synthesis, structure, theoretical calculations and biological activity of sulfonate active ester new derivatives

, By:Ghazzali, M ; Khattab, SAN; Elnakady, YA ; Al-Mekhlafi, FA ; Al-Farhan, K ; El-Faham, A . 2013

Abstract

A series of naphthyl and tolyl sulfonate ester were synthesized and characterized by H NMR. X-ray single crystal diffraction experiments established the molecular structure of three new sulfonate esters derivatives, and spectral data agree with these in solution. The observed hydrogen bonding is discussed on the basis of crystal structural analyses and DFT/MP2 geometry optimization quantum calculations. Antimicrobial activities were screened for selected compounds against three human cancer cell lines and Mosquito Culex pipiens larvae. (c) 2013 Elsevier B.V. All rights reserved.

Volume Number

1046

Magazine \ Newspaper

JOURNAL OF MOLECULAR STRUCTURE

Pages

147-152

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