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Iftekhar Md Hassan

Associate Professor

Associate Professor

كلية العلوم
AB-73/1', Ground Floor, Building 5, College of Sciences, Dariyah, KSU
السيرة الذاتية

CV-Iftekhar Hassan

مختصر السيرة الذاتية
I am an Assistant Professor in the Department of Zoology, College of Science, King Saud University, Riyadh. Being a scientist, I want to contribute my knowledge in the fields of cancer, clinical toxicology, metabolic disorders and immunology for the betterment of the society. Besides, I am also enthusiastic to share my knowledge and experience with the new generation to prepare them to face upcoming challenges in Biological Sciences. Moreover, I shall try my best to contribute with my knowledge, skills and experience to enhance the reputation and growth of my institute in every possible manner.
نص السيرة الذاتية

Dr. Iftekhar MD Hassan

                                                          
 

Departmental Address:
Lab: Department of Zoology, College of Science, King Saud University,  P.O.Box 2455; Riyadh, Saudi Arabia- 11451
E-mail:
iftekharhassan2002@gmail.com;
Institutional E-mail:
ihassan@ksu.edu.sa
Phone: 00966-114676547
 

 

                                         
                                             

OBJECTIVE

 I am an Assistant Professor in the Department of Zoology, College of Science, King Saud University, Riyadh. Being a scientist, I want to contribute my knowledge in the fields of cancer, clinical toxicology, metabolic disorders and immunology for the betterment of the society. Besides, I am also enthusiastic to share my knowledge and experience with the new generation to prepare them to face the upcoming challenges in Biological Sciences. Moreover, I shall try my best to contribute with my knowledge, skills

and experience to enhance the reputation and growth of my institute in every possible manner.
 

Profile

  

 

  • Principal investigator of one project (project no. M S 67-36) and co-investigator (project no. A T 19-35) in another two projects (KCAST funded) and Deanship of Scientific Research (RGP- 1436-004; KSU funded) research based cancer treatment and toxicology.

 

  • I have been taking lab classes of graduation and post-graduate (Master) students for the last four years for general biochemistry, physiology and endocrinology courses in zoology (ZOO-109; ZOO-332, ZOO-432, ZOO-435, ZOO-531, ZOO-534). Recently, I have been assigned to theory class of Pre-Medical Biology course ZOO-109.

 

  • Doctoral experience in amelioration of anticancer drug, cisplatin induced toxicities by riboflavin in vivo within collaborative laboratory environment covering research areas including oncology, stress biology, photobiology, clinical toxicology and histopathology.

 

  • Publication record includes 28 research papers in the high impact factor ISI-indexed journals of International repute.

 

  • Have proposed a novel interaction mechanism between cisplatin and riboflavin in vivo leading to blunting of cisplatin-induced side effects, a chemoradiotherapy based strategy to improve cancer treatment with better efficacy and fewer side effects.

 

  • Have been in the team exploring pro-oxidant potential and mechanism of the major anticancer drugslike Methotrexate, 5-Fluorouracil and cyclophosphamide in vitro in the presence of riboflavin and copper under photoillumination.

 

  • Have contributed in exploring pharmaceutical and antioxidant aspects of natural toxins (e.g.-Samsum ant venom).

 

Academic Qualifications

 
September, 2013-   Assistant Professor and post-doc researcher in the Department of Zoology, King Saud University, Riyadh, Saudi Arabia.
 
2012                      Ph.D.  (Biochemistry) awarded
Thesis title: ‘In vivo studies on riboflavin-cisplatin interactions’
                              Advisor: Prof. ImranaNaseemfrom Aligarh Muslim University, Aligarh (India)
 
2007                      Mater of Science (Specialization in Biochemistry) with 71%
Dissertation Title: “Effect of photoilluminated riboflavin onto cisplatin induced oxidative stress in vivo”.
Advisor: Prof. ImranaNaseemfrom Aligarh Muslim University, Aligarh (India)
 
2005                      Bachelor in Science (Honor) in Biochemistry

with 70.6%
from Aligarh Muslim University, Aligarh (India)                        
 
2001                      Intermediate in Science (Physics, Chemistry and
Biology stream)with 87.5%  from Ram Mohun Roy Seminary +2, Patna (Bihar Intermediate Education Council, Bihar, India)
 
1999                      Matriculation with 73.2%
from National High School, Kishanganj (Bihar School Examination Board, Patna, Bihar, India)

Professional Qualifications

 

  • UGC-BSR Scholarship (April, 2010-March, 2012) for being among top 5 research students in the departmentfrom the University Grants Commission, India.

  • UGC Non-NET fellowship (November, 2007-March, 2010) from the University Grants Commission, India.

  • Qualified National level graduate aptitude test in Engineering (GATE) in 2007 with 86.68 percentile conducted by Internationally renowned Indian Institute of Technology (IIT), Government of India.

  • Qualified written test (2005) of National Center for Biological Sciences, Bengaluru, India.

  • Student’s scholarship (2003, 2004), Aligarh Muslim University, Aligarh, India.

  • Bharat Seva Trust Scholarship (2002), Government of U.P., India.

  • Numerous district and state level awards during Intermediate and matriculation

 

 
 
TEACHING EXPERIENCE

 

  • Working as an assistant professor teaching graduate and post graduate students of life science and allied sciences (for lab courses: ZOO-332, ZOO-432, ZOO-531, ZOO-534) in King Saud University since September, 2013.

 

  • Have been research assistant in Department of Biochemistry, Faculty of Life Sciences, Aligarh Muslim University, Aligarh, U.P., India (2012-2013).

 

  • Have taken practical classes (assigned to Prof. Imrana Naseem) at graduation and post-graduation level at Department of Biochemistry, Faculty of Life Sciences, Aligarh Muslim University, Aligarh, U.P., India (2010-2012).

 

  • Have trained 4 post-graduate students in their minor research projects assigned to Prof. Imrana Naseem at Department of Biochemistry, Faculty of Life Sciences, Aligarh Muslim University, Aligarh, U.P., India (2009-2012).

 

RESEARCH PUBLICATIONS

 
Research Articles (in International peer-reviewed journals)
 
1.  Restrained management of copper level enhances the antineoplastic activity of imatinib in vitro and in vivoIftekhar Hassan, Azmat Ali Khan, Shazia Aman, Wajhul Qamar, Hossam Ebaid, Jameel Al-Tamimi, Ibrahim M. Alhazza, Ahmed Rady. Scientific Reports (Accepted on 27th December 2017) (Impact Factor: 4.6

2.  Bio-fabrication of Zinc oxide nanoparticle from Ochradenus baccatus leaves: broad-spectrum anti-biofilm activity, protein binding studies, in vivo toxicity and stress studies. Nasser Al-Shabib, Fahad Mabood Hussain, Iftekhar Hassan, Mohd Khan, Faheem Ahmed, Faizan Qais, Mohammad Oves, Mashihur Rahman, Rais Ahmad Khan, Altaf Khan, Ibrahim M Alhazza, Shazia Aman, Saba Noor, Hossam Ebaid, Jameel Al-Tamimi, Javed Masood Khan, Abdul Al-Ghadeer, Khurshid Alam Khan, Iqbal Ahmad and Afzal Hussain. Journal of Nanomaterials (Accepted on 25th December 2017) (Impact Factor: 1.81)
 
3. Age affects the mitigating efficacy of riboflavin against cisplatin-induced toxicity in vivo. Hassan INaseem IAman SAlhazza IM. Nutrition and Cancer 68 (2016):1381-1393. (Impact factor: 2.3) 
 

4.    Biogenic synthesis of zinc oxide nanostructures from Nigella sativa seed: Prospective role as food packaging material inhibiting broad-spectrum quorum sensing and biofilm. Al-Shabib NAHusain FMAhmed FKhan RAAhmad IAlsharaeh EKhan MSHussain ARehman MTYusuf MHassan IKhan JMAshraf GMAlsalme AMAl-Ajmi MFTarasov VVAliev G. Scientific Reports (2016);6:36761. DOI: 10.1038/srep36761. (Impact factor: 5.2)

 

5.    Wound healing of different molecular weight of hyaluronan; in-vivo study.Fouda MMAbdel-Mohsen AMEbaid HHassan IAl-Tamimi JAbdel-Rahman RMMetwalli AAlhazza IRady AEl-Faham AJancar J. International Journal Biological Macromolecules 89(2016)582-591. doi: 10.1016/j.ijbiomac.2016.05.021. (Impact factor: 3.1)

 

6. Broad-spectrum inhibition of AHL-regulated virulence factors and biofilms by sub-inhibitory concentrations of ceftazidime. FM Husain, I Ahmad, MH Baig, MS Khan, MS Khan, Iftekhar Hassan and Nasser Abdulatif Al-Shabib. Royal Society of Chemistry Advance 6 (2016)27952-27962. DOI: 10.1039/C6RA02704K (Impact factor: 3.21; Citations: 2)
 

 7. Targeted nano-delivery of novel omega-3 conjugate against hepatocellular carcinoma: Regulating COX-2/bcl-2 expression in an animal model. Azmat Ali Khan , Amer M. AlanaziMumtazJabeenIftekhar HassanMashooq Ahmad Bhat. Biomedicine & Pharmacotherapy. 81(2016) 394–401 (Impact factor:2.3)

 

8. Protective effect of riboflavin on cisplatin induced toxicities: A gender-dependent study.I Naseem, I Hassan*( as Corresponding author), IM Alhazza, S Chibber - Journal of Trace Elements in Medicine and Biology 29 (2015) 303-314 (Impact factor: 2.5, Citations:5)

 

9. Riboflavin Arrests Cisplatin-Induced Neurotoxicity by Ameliorating Cellular Damage in Dorsal Root Ganglion Cells. M Salman, I Naseem, I Hassan *(as Corresponding author), AA Khan, IM Alhazza.BioMed research international, 2015, Article ID 603543, 5 pages. http://dx.doi.org/10.1155/2015/6035432015 (Impact factor: 2.12; ; Citations: 1)

 

10. Camel milk peptide improves wound healing in diabetic rats by orchestrating the redox status and immune response. H Ebaid, B Abdel-Salam, I Hassan, J Al-Tamimi, M Ali, I Alhazza. Lipids in Health and Disease 14 (2015) 132. DOI:10.1186/s12944-015-0136-9 (Impact factor: 2.21; Citations: 1)

 

11. Antigenotoxic and Antioxidative Effects of Novel Anticancer Conjugate on Doxorubicin Induced Toxicity in Mice. M Jabeen, MA Amer, I Hassan, M Afzal, A Azmat. Lat Am J Pharm.2015; 34(1):101-108 (Impact factor: 0.35

 

12. Antioxidant bioactivity of samsum ant (Pachycondylasennaarensis) venom protects against CCl4-induced nephrotoxicity in mice. HossamEbaid, Jameel Al-Tamimi, Iftekhar Hassan, Ibrahim M Alhazza, Mohamed Al-Khalifa. Oxidative Medicine and Cellular Longevity. 2014, Article ID 763061, 8 pages http://dx.doi.org/10.1155/2014/763061. (Impact Factor: 4.49; Citations: 5)

 

13. Zinc improves the immune function and the proliferation of lymphocytes in Cadmium-treated rats. HossamEbaid, Iftekhar Hassan, Samir Bashandy, Nael Abu Taha, Amer Mahmood, Suliman Alomar, Ibrahim Alhazza, Ashraf Mashaly, Ahmed Rady. Central European Journal of Immunology 2014; 39 (4): 441-448. (Impact factor 0.35, Citations:1)

 

14. Riboflavin alleviates cisplatin induced neurotoxicity in vivo under photoillumination. Iftekhar Hassan, Sandesh Chibber, Aijaz A Khan, Imrana Naseem. Cancer Biotherapy and Radiopharmaceuticals28 (2013) 160-168. (Impact Factor: 1.7; Citations: 11)

 

15. White light augments chemotherapeutic potential of cyclophosphamide: An in vitro study.  SandeshChibber, Iftekhar Hassan, Maria Salman, Imrana Naseem. Biometals26 (2013) 23-31. (Impact factor: 2.1; Citations:2)

 

16. Riboflavin ameliorates cisplatin induced toxicities under photoillumination. Iftekhar Hassan, Sandesh Chibber, Aijaz A Khan, Imrana Naseem. Plos One7(5):(2012) e36273. [doi:10.1371/journal.pone.0036273]. (Impact Factor: 3.2; Citations: 27)

 

17. Light-mediated interaction of methotrexate with transition metal Cu (II).SandeshChibber, Iftekhar Hassan, Mohd Farhan, Imrana Naseem. Medicinal Chemistry Research 21 (2012)2379-2387. (Impact Factor: 1.4; Citations: 6)

 

18. In vitro pro-oxidant action of Methotrexate in presence of white light. Sandesh Chibber, Iftekhar Hassan, Mohd Farhan, Imrana Naseem. Journal of Photochemistry and Photobiology B: Biology 104 (2011) 387–393. (Impact Factor: 3.0; Citations: 7)

 

19. White light-mediated Cu (II)–5FU interaction augments the chemotherapeutic potential of 5-FU: an in vitro study. Sandesh Chibber, Mohd Farhan, Iftekhar Hassan, Imrana Naseem. Tumour Biology 32 (2011) 881-892. (Impact Factor: 2.91; Citations: 10)

 

20. Ameliorative effect of riboflavin on the cisplatin induced nephrotoxicity and hepatotoxicity under photoillumination. Hassan I, Chibber S and Naseem I. Food and Chemical Toxicology 48 (2010) 2052–2058. (Impact Factor: 3.5; Citations: 34)

 
Review Articles (in International peer-reviewed journals)

21. Galectins - a potential target for cardiovascular therapy. Ashraf GMPerveen AZaidi SKAhmad AShakil SFiroz CKJabir NRHassan IKhan TAYarla NSTabrez S. Current Vascular Pharmacology (2017).15 (4); DOI : 10.2174/1570161115666170201113046 (Impact Factor: 2.3)

 

22. Recent updates on the dynamic association between oxidative stress and neurodegenerative disorders. A. Khan, Taqi; Hassan, Iftekhar; Ahmad, Ausaf; Perveen, Asma; Aman, Shazia; Quddusi, Saima; M. Alhazza, Ibrahim; M. Ashraf, Ghulam; Aliev, Gjumrakch. CNS & Neurological Disorders - Drug Targets 2016; 15(3): 310-320 (Impact factor: 3.1)

 

23. Certain Phase I and II Enzymes as Toxicity Biomarker: An Overview. Iftekhar Hassan, Nasimudeen R. Jabir, Saheem Ahmad, Aaliya Shah, Shams Tabrez. Water, Air, & Soil Pollution2015; 226:153. (Impact factor: 1.55)

 

24. An Overview on Global Trends in Nanotechnological Approaches for Alzheimer Therapy. Shams Tabrez, Nasimudeen R Jabir, CK Firoz, Saheem Ahmad, Iftekhar Hassan, Athanasios Alexiou, Mohammad Amjad Kamal. Current Drug Metabolism. 2015; 16,719-727 (Impact factor: 3.5; Citations: 2)

 

25. Protein misfolding and aggregation in Alzheimer's disease and type 2 diabetes mellitus.Ashraf GM, Greig NH, Khan TA, Hassan I, Tabrez S, Shakil S, Sheikh IA, Zaidi SK, Akram M, Jabir NR, Firoz CK, Naeem A, Alhazza IM, Damanhouri GA, Kamal MA. CNS NeurolDisord Drug Targets.2014;13(7):1280-93. (Impact factor: 3.1; Citations: 12)

 

26. Vitamin B2: a promising adjuvant in cisplatin based chemoradiotherapy by cellular redox management. Iftekhar Hassan, Sandesh Chibber, Imrana Naseem. Food and Chemical Toxicology 59 (2013)715-723. (Impact Factor: 3.5; Citations: 10)

 

27. Novel aspect of chemophototherapy in treatment of cancer. Sandesh Chibber, Iftekhar Hassan, Imrana Naseem. Tumour Biology 33 (2012) 701-706. (Impact Factor: 2.9; Citations: 9)

 
Under communication
 

1. SAV exerts anti-tumor activity via triggering immunomodulation against cancer: in vitro as well as in vivo. Hossam Ebaid, Jameel Al-Tamimi, Iftekhar Hassan, Ibrahim M Alhazza et al. (2017)

 

2. Biosurfactant nanofibers for clean-up of oil spill with minimal side effects on rat animal models. HossamEbaid, Jameel Al-Tamimi, Iftekhar Hassan, Ibrahim M Alhazza et al. (manuscript under communication, 2016)

 

3. Higher expression of CD80 and CD86 on polymorphnuclear neutrophils in the remodeling phase of wound healing in diabetic rats: An improvement by a small peptide extracted from Saudi camel milk. HossamEbaid, Jameel Al-Tamimi, Iftekhar Hassan, Ibrahim M Alhazza et al. (manuscript in preparation, 2016)

 

Book Chapters

1. Aliev G, Horecky J, Vancova O, Ashraf GM, Hassan I, Bragin V, Shevtsova E, Klochkov SG, Kosenko EZ et al. The three vessel occlusion as a model of vascular dementia: oxidative stress and mitochondrial failure as an indicator of brain hypoperfusion. In: Laher, Ismail (Ed.) Systems Biology of Free Radicals and Antioxidants, pp. 2023-2032, Springer Berlin Heidelberg (2014)

 

2. Hassan I and Naseem I. Natural photosensitizer with established anticancer drugs: A novel photodynamic strategy to improve anticancer chemoradiotherapy. (In preparation)

Other Curricular Activities

 
Oral Presentations

  • ‘Emerging trends in Biological Sciences: Special Emphasis on Neurosciences’ (September 24-25th, 2012) at Interdisciplinary Brain Research Center, Faculty of Medicine, Aligarh Muslim University, Aligarh, India-202002.

  • NANO-2 (March 10-12th, 2012), Department of Applied Physics, Z. H. College of Engineering, Aligarh Muslim University, India.

  •  

  • MAASCON-1, First Annual National Symposium of the Muslim Association for the Advancement of Science (MAAS), Frontiers in Life sciences: Basic and Applied under abstract no. 83 (23-24th October, 2010), Department of Zoology, Aligarh Muslim University, India.

 
Workshops attended

  • National workshop on ‘Scientific/ Research paper writing’ (April 5-7th, 2013) organized by The National Academy of Sciences, India at MohanlalSukhadia University, Udaipur, India.

  • International workshop ‘Liver Fluke: an RNAi workshop’ (February 11-12th, 2013) combined organized by Queen University of Belfast (UK) and Aligarh Muslim University, India.

  • Interaction Programme on Research Methodology in Biological Sciences’ (December 14th to 6th of January, 2011) organized by UGC  Academic Staff College, Aligarh Muslim University, India.

  • Environsense’ (10thOctober, 2010) organized by Z.H. College of Engineering and Technology, Aligarh Muslim University, India.

  • Recent Advances in Biochemistry’ (February 8th to 9th, 2010) organized by UGC -Academic Staff College, Aligarh Muslim University, India.

  • Comet Assay training (October 26-30th,2010) at Indian Institute for Toxicological Research (IITR), Lucknow, India.

 
Poster Presentations
 
·      Attended “International Conference on recent advances in chemical sciences” organized by Department of Chemistry, Faculty of Sciences, Aligarh Muslim University, Aligarh 202002, U. P., India (March 29-30, 2016).
 
·      3rd Annual Meeting of Indian Academy of Biomedical Sciences & Symposium on ‘Modern Trends in Human Diseases’
organised by Department of Biochemistry, Faculty of Medicine, J. N. Medical College, Aligarh Muslim University, Aligarh 202002, U. P., India (December 14-15, 2013).

  • 2nd prize for poster presentation in ‘Emerging trends in Biological Sciences: Special Emphasis on Neurosciences’ at Interdisciplinary Brain Research Center, Faculty of Medicine, Aligarh Muslim University, Aligarh, India-202002 (September 24-25th, 2012).

 

  • 10th Annual Research Festival ‘Biospark-2012’ organized by School of Life Sciences, Jawaharlal Nehru University, New Delhi, India (March 14-15th, 2012).

 

  • National Symposium on ‘Current Trends in Biochemical, Biomedical and Environmental Sciences’ under the auspices of UGC-DRS II Programme organized by Department of Biochemistry, Life Sciences, Aligarh Muslim University, Aligarh, U.P., India (February 22nd, 2011).

 

  • National Symposium on ‘Recent Trends in Enzyme Technology, Toxicology and Bioinformatics’ under the auspices of UGC-DRS II Programme organized by Department of Biochemistry, Life Sciences, Aligarh Muslim University, Aligarh, U.P., India (March 3rd, 2010).

 

  • International SFRR Satellite Symposium ‘Free Radicals in Health and Disease’ under the auspices of SFRR and UGC-DRS II Programme under poster no. 38 organized by Department of Biochemistry, Life Sciences, Aligarh Muslim University, Aligarh, U.P., India, (March 17-18th, 2009).

 

  • ‘Advances in Clinical Biochemistry-Biomarkers, Molecular Diagnosis and Quality Assurances &Ist U.P. Chapter of Association of Clinical Biochemists of India (UPACBICON 2008)’ organized by Department of Biochemistry, JNMCH, Aligarh Muslim University, Aligarh, U.P, India (November 15-16th, 2008).

 

  • National Symposium on ‘Recent Advances in Biochemistry and Allied Sciences’ under the auspices of UGC-DRS-II Programme organized by Department of Biochemistry, Life Sciences, Aligarh Muslim University, Aligarh, U.P., India (March 25th, 2008).

 

  • International Symposium on the Preventive and Mechanistic Mutagenesis & XXXIII EMSI Annual Meeting’ under Abstract No. P-44 organized by Department of Agricultural Microbiology, Aligarh Muslim University, Aligarh, U.P, India, (January 1-3rd, 2008).

 

 

Personal Information

 

Name                     :           Dr. Iftekhar Hassan
Father’s name        :           Md. Hassan
Date of birth           :           14th January, 1985
Gender                   :           Male
Nationality             :           Indian
Language proficiency:        English, Hindi and
Urdu.
Soft skills:                         MS office, Statistical Analysis, Adobe, Expert with internet and browsing.
Permanent Address:           Kishanganj, Bihar, India-855108.

 
Referees

On request.
 
 
I, hereby declare that all information furnished above is true to the best of my knowledge.
 
 
Dr. Iftekhar Md Hassan

 

الجامعه
Aligarh Muslim University, Aligarh, India
من تاريخ
الي تاريخ
التخصص
Biochemistry
الدرجة
B.Sc., M.Sc., PhD