Appointments and Publications for Saadeldin IM

Islam M. Saadeldin has received his Ph.D. degree from Seoul National University, South Korea. He was a visiting scholar at Niigata University, Japan. He has more than 25 SCI papers covering the field of advanced reproductive biotechnology such as somatic cell nuclear transfer (SCNT), therapeutic cloning, genome editing (TALENs and CRISPR/Cas9), transgenesis and assisted reproductive techniques (ARTs) as well as parthenogenesis and embryonic stem cells applications. In addition, elucidating the roles of exososmes in embryonic-maternal crosstalk. You can follow me on: & &

1. Saadeldin IM, Chandriani K, Kim SJ, Mooh JH, El-Maadly E, Lee BC. 2016 Blastocysts derivation

from somatic cell fusion with premature oocytes (Prematuration somatic cell fusion).

Development, Growth and Differentiation 58 (2): 157-166, (IF: 2.47) (DOI: 10.1111/dgd.12264).
2. Hussein MH. Ali HA. Saadeldin IM, Ahmed MM. 2016 Querectin Alleviates Zinc Oxide Nanoreprotoxicity in Male Albino Rats. J Biochem Molecular Toxicology. (IF:1.9) (DOI: 10.1002/jbt)
3. Abdelfattah-Hassan A, Saadeldin IM, Ghonimi W (2016): Optimization of the isolation process of putative bovine mammary stem cells. The Japanese journal of veterinary research, 64:S65-S71 (IF: 0.27)

4. Saadeldin IM, Oh HyunJu, Lee BC (2015): Embryonic-maternal crosstalk via exosomes: Potential implications (Opinion). J Stem Cells & Cloning, 8:103-107

5. Oh HJ, Kim GA, Rhee SH, Kim MJ, Saadeldin IM, Lee BC (2015): Age-dependent Alteration of

Transgene Expression and Cytomegalovirus Promoter Methylation in Transgenic Cloned and

Recloned Dogs. Molecular Reproduction and Development 82(5):330-331 (IF: 2.675) DOI


6. Saadeldin IM, Kim SJ, Lee BC (2015): Blastomere aggregation as an efficient alternative for

trophoblast culture in pocine parthenotes. Development, Growth and Differentiation 57(5):362-

368 (IF:2.47) (doi: 10.1111/dgd.12215)

7. Kim SJ, Moon JH, da Torre BR, Saadeldin IM, Lee BC, Jang G (2015): Oct4 overexpression

Facilitates Proliferation of Porcine Fibroblasts and Development of Cloned Embryos. 23(5):704-711,

Zygote (IF: 1.241) (DOI:

8. Saadeldin IM, Kim SJ, Choi YB, Lee BC (2014): Improvement of cloned embryos development by

co-culturing with parthenotes: a possible role of exosomes/microvesicles for embryos paracrine

communication. Cellular Reprogramming. 16(3):223-234 (IF: 2.744) (doi:10.1089/cell.2014.0003).

9. Jung-Taek Kang, Joon Ho Moon, Ji-Yei Choi, Sol Ji Park, Su Jin Kim, Islam M. Saadeldin, Byeong

Chun Lee (2016): Effect of antioxidant flavonoids (Quercetin and Taxifolin) on in vitro maturation of

porcine oocytes. Asian-Australasian J. Animal Science, 29(3): 352-358 (IF:


10. Saadeldin IM, Oh HJ, Lee BC (2015): Improvement of cloned embryos development by co-

culturing with parthenotes using microdrop culture system. Cloning & Transgenesis 4:e117. (doi:


11. Saadeldin IM (2015): Cloning and its Applications (Editorial). Cloning & Transgenesis, 4:e118.

(doi: 10.4172/2168-9849.1000e118).

12. Saadeldin IM (2015): Transgenesis through blastomeres transfection (Clinical image). Cloning

& Transgenesis, 4:i103. (doi: 10.4172/2168-9849.1000i103).

13. Saadeldin IM, Kim SJ, Choi YB, Lee BC (2014): Post-maturation zona perforation improves

porcine parthenogenetic trophoblast culture. Placenta 35(4):286-288 (IF: 3.117).

14. Saadeldin IM, Koo OJ, Kang JT, Kwon DK, Park SJ, Kim SJ, Moon JH, Oh HJ, Jang G, Lee BC

(2012): Paradoxical effects of kisspeptin: it enhances oocytes in vitro maturation while it has an

adverse impact on hatched blastocysts during in vitro culture. Reproduction, Fertility and

Development 24(5):656-668 (IF: 2.553).

15. Saadeldin IM, Kim BH, Lee BC and Jang G (2011): Effect of different culture media on the

temporal gene expression in the bovine developing embryos. Theriogenology 75(6):995-1004 (IF:


16. Saadeldin IM, Choi WJ, da Torre BR, Kim BH, Lee BC, Jang G (2012): Embryonic development

and implantation related gene expression of reconstructed oocyte with bovine trophoblast cells.

Journal of Reproduction and Development 58(4):425-431 (IF: 1.637).

17. Kim SJ, Saadeldin IM, Lee SJ, Lee WW, Kim BH, Lee BC and Jang G (2011): Production of transgenic bovine cloned embryos using piggybac transposition. J. Vet. Med. Sci. 73(11): 1453–

1457 (IF: 0.722) (*equally contributed 1stauthors).

18. Saadeldin IM, Ali MF, Hamada MZ, El-Badry AA (2011): Effects of exposure to 50 Hz, 1 Gauss

magnetic field on reproductive traits in male albino rats. Acta Vet Brno 80(1):107-111 (IF: 0.534).

19. Saadeldin IM, Elsayed A. Kim SJ, Moon JH, Lee BC (2015): A spatial model showing differences

between juxtacrine and paracrine mutual oocyte-granulosa cells interactions. Ind. J. of

Experimental Biology. 53(2), 75-81 (IF: 0.75).

20. Kwon DK, Saadeldin IM, Koo OJ, Park SJ, Kang JT, Park HJ, Kim SJ, Moon JH, Jang G, and Lee BC

(2014): Optimizing Electrical Activation of Porcine Oocytes by Adjusting Pre- and Post- Activation

Mannitol Exposure Times. Reprod Domest Anim 49(6): 995-999 (IF: 1.117) (DOI: 10.1111/rda.12420).

21. Park JE, Kim MJ, Ha SK, Hong SG, Oh HJ, Kim GA, Park EJ, Kang JT, Saadeldin IM, Jang G, Lee BC

(2012): Altered cell cycle gene expression and apoptosis in post-implantation dog parthenotes.

PloS one 7(8):e41256. (IF: 3.5).

22. Moon JH, Kim SJ, Park HJ, Kang JT, Park SJ, Koo OJ, da Torre BR, Saadeldin IM, Lee BC, Jang G

(2012): Production of porcine cloned embryos derived from conditionally exogenous gene

expressing cells using Cre-l ox P. Zygote. 20(4):423-425. (IF: 1.241).

23. Choi JY, Kang JT, Park SJ, Kim SJ, Moon JH, Saadeldin IM, Jang G, Lee BC (2013): Effect of 7,8-

Dihydroxyflavone as an Antioxidant on In Vitro Maturation of Oocytes and Development of

Parthenogenetic Embryos in Pigs. J Reprod Develop. 59(5):450-456 (IF: 1.637).

24. Kim SJ, Moon JH, da Torre BR, Saadeldin IM, Kang JT, Choi JY, Park SJ, Lee BC, Jang G (2013):

DsRed gene expression by doxycycline in porcine fibroblasts and cloned embryo using transposon.

Afr J Biotechnology 12(21): 3188-3190. (IF: 0.57).

25. Oh HJ, Saadeldin IM, Lee BC (2013): Toward A Transgenic Dog as a Human Disease Model. J

IVF Reprod Med Genet 1: e102. (doi:10.4172/ jfiv.1000e102)

26. Saadeldin IM, Fadel MA, Hamada MZ and El-Badry AA (2008): Hazards from exposure to 50 Hz,

1 Gauss magnetic field on reproduction in male albino rats. Egypt J Basic Appl Physiol, 7(1): 85-97.

27. Magdeldin S, Ismail T, Saadeldin I, and Yamamoto T (2008): Dehydration- inducible changes on

the genetic expression of aquaporin family in C57BL/6J mice. Egypt J Basic Appl Physiol, 7(S1): 35-51.