Toxicology and Carcinogenesis BCH 454

Topics
Course Introduction, mechanism and categorizing of carcinogens
Metabolism of toxic substance and carcinogens.
Human exposure to carcinogens-Occupational cancer
First continuous exam (30%)
Molecular principles of specific toxicants
Food additive and carcinogens and  recent topics in carcinogens
Second continuous exam (30%)
Mycotoxins as carcinogens
Xenobiotic-induced Methoglobinemia and biotransformation
Toxicology of oxygen
Physical agents in carcinogenesis
Covalent binding of Xenobiotic to DNA and protein