BCH 454 Toxicology & Carcinogens

Course Introduction, mechanism and categorizing of carcinogens

Metabolism of toxic substance and carcinogens.

Human exposure to carcinogens-Occupational cancer

First continuous exam (30%)

Molecular principles of specific toxicants

Food additive and carcinogens and  recent topics in carcinogens

Second continuous exam (30%)

Mycotoxins as carcinogens

Xenobiotic-induced Methoglobinemia and biotransformation

Toxicology of oxygen

Physical agents in carcinogenesis

Covalent binding of Xenobiotic to DNA and protein