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Prof. Khalid Abdullah Al-Ghanem

Professor

Aquatic Ecology and Toxicology

كلية العلوم
أب ٦٨
المنشورات
فصل كتاب
2017
تم النشر فى:

Structural Changes in Chromosomes

Al-Ghanim, Abdul Rauf Shakoori, Saira Aftab, and Khalid . 2017

Chromosomal aberrations • Deletion • Duplication • Inversion • Translocation • Genetic imbalance • H

Chromosomes can be structurally identified by their sizes, positions of centromeres
and nucleolar organizers, and patterns of chromomeres, heterochromatin,
and bands. There are four types of aberrations in the chromosomal structure such
as deletions, duplications, inversions, and translocations which can be detected
cytologically under the microscope. Some changes are however too subtle to be
detected cytologically. Deletions represent missing segments of chromosomes.
The homozygous deletions can be lethal, whereas heterozygous deletions can be
nonlethal or lethal and can express recessive genes uncovered by deletion.
Duplications can cause an imbalance in the genetic material, thereby producing
phenotypic effect in the organism and leading to increased variety of gene functions.
Inversions are caused by 180 degree turn of a segment of a chromosome,
which cause little problem for an organism under homozygous condition, but
inversion heterozygotes often have pairing difficulties during meiosis, leading to
formation of inversion loops. Crossing over within loops usually results in inviable
products. The crossover products will be different for pericentric and paracentric
inversions. Translocations involve relocation of a chromosomal segment
to another position in the genome. In heterozygous state, the translocations produce
duplication-deletion meiotic products, which can lead to unbalanced
zygotes, and new gene linkages. Chromosome rearrangements can cause ill
health in human population – infertility and mental retardation being the dominant
effects.

نوع عمل المنشور
Chromosomal aberrations • Deletion • Duplication • Inversion • Translocation • Genetic imbalance • Heterochromatin • Interstitial deletion • Ring chromosome • Cri-du-chat syndrome • Angelman syndrome • Beckwith-Wiedemann syndrome • Down syndrome • Prader-
اسم الناشر
Tariq Ahmad Bhat • Aijaz Ahmad Wani Editors
مدينة النشر
Springer (India)
الصفحات
245 - 274
مزيد من المنشورات
publications

This current work revealed a single-step fabrication of tungsten oxide nanoflakes (WO3
NFs) with the help of Terminalia arjuna bark extract. Bioactive phytoconstituents of T. arjuna bark…

بواسطة Sarinthip Thanakkasaranee 1, Gopinath Kasi 1,*, Sivasamy Kadhiravan 2 , Ayyakannu Arumugam 3, Khalid A. Al-Ghanim 4, Mian Nadeem Riaz 5 and Marimuthu Govindarajan 6,7,*
2023
تم النشر فى:
Sarinthip Thanakkasaranee 1, Gopinath Kasi 1,*, Sivasamy Kadhiravan 2 , Ayyakannu Arumugam 3, Khalid A. Al-Ghanim 4, Mian Nadeem Riaz 5 and Marimuthu Govindarajan 6,7,*
publications

In the present work, the residual biomass of the green seaweed Ulva lactuca was chosen as feedstock to undergo separate
hydrolysis and fermentation process to produce bioethanol. The…

بواسطة Kalavathy Gengiah a,1, Naveenkumar Rajendran b,c,1, Khalid A. Al-Ghanimd, Marimuthu Govindarajan e,f, Baskar Gurunathan a,⁎
2023
تم النشر فى:
Kalavathy Gengiah a,1, Naveenkumar Rajendran b,c,1, Khalid A. Al-Ghanimd, Marimuthu Govindarajan e,f, Baskar Gurunathan a,⁎
publications

Waterbirds may be a good indicator of harmful metal levels in aquatic environments. Waterbirds’
organs and tissues were tested for the presence of pollutants, such as metals. However,

بواسطة Jeganathan Pandiyan 1, Arumugam Poiyamozhi 1, Shahid Mahboob 2, Khalid A. Al-Ghanim 2, Fahad Al-Misned 2, Zubair Ahmed 2, Irfan Manzoor 3 and Marimuthu Govindarajan 4,5,*
2022
تم النشر فى:
Jeganathan Pandiyan 1, Arumugam Poiyamozhi 1, Shahid Mahboob 2, Khalid A. Al-Ghanim 2, Fahad Al-Misned 2, Zubair Ahmed 2, Irfan Manzoor 3 and Marimuthu Govindarajan 4,5,*