A High-Resolution Hand held Hybrid Camera for Gamma and Optical Imaging

Conference Paper

Lees, Dr. John . 2015

• نوع عمل المنشور: Poster presentation
• اسم المؤتمر: The British Nuclear Medicine Society (BNMS) Autumn
• عنوان المؤتمر: Royal Society of Medicine, London
• تاريخ المؤتمر: الأربعاء, أيلول (سبتمبر) 2, 2015

مستخلص المنشور

A combination of an optical and a gamma camera, in a co-aligned configuration, offers high spatial resolution multi-modal imaging giving a superimposed scintigraphic and optical image. The hybrid Gamma Camera offers new possibilities for assisting surgeons and interventionists with intraoperative molecular imaging.
Methods: We have developed a compact hybrid gamma-optical camera consisting of a 0.6mm thick CsI(Tl) columnar scintillator coupled to an electron multiplying CCD. A 1.0mm diameter pinhole collimator produces a 40x40mm nominal field of view (FOV) and alignment of an optical camera provides the same FOV as the gamma camera for image superimposition.
Images are recorded simultaneously and presented in a fused display. The performance characteristics including sensitivity, spatial resolution and count rate response, were measured based on NEMA protocols adapted for use with small FOV systems.
Results: The characteristics of the hybrid camera compared favourably with other portable cameras currently available. Spatial resolution ~1.5 mm (at 10mm) was recorded with system sensitivity of up to 214cps/MBq. Initial laboratory phantom simulations and clinical investigations  demonstrated a new way of visualising uptake, with good localisation of the site of activity in patients.
Conclusion: The anatomical context provided by the optical camera aids the physical localisation of radiopharmaceutical uptake in patients. The compact size and fused display makes the system ideal for surgical use, where optical information can aid localisation of sites of uptake, e.g. in sentinel node detection. Recent improvements to the camera system along with results of phantom and clinical imaging are reported.