A high-resolution gamma-optical hybrid camera for medical imaging
Introduction
The development of portable mini gamma cameras in medical imaging offers new applications for intraoperative nuclear imaging. A new concept for a nuclear diagnostic imaging is presented, Hybrid Compact Gamma Camera (HCGC). This newly developed gamma camera is a Small Field Of View (SFOV) camera and has high spatial resolution, approximately 1mm. The camera was originally developed in Space Research Centre, University of Leicester. This study investigates the performance of the HCGC following characterisation protocols modified for use specifically with SFOV gamma cameras.
Materials and methods
The Hybrid Compact Gamma Camera (HCGC) is a new portable gamma camera and has the potential to be operated as a hand-held camera during intraoperative procedures. Figure 1 shows that the CGC consists of charged coupled device (CCD), a thallium-doped caesium iodide CsI(TI) scintillator and a tungsten pinhole collimator. The distance between the CCD and the pinhole collimator is 10mm which is fixed. While the distance between the pinhole collimator and the source being imaged is varied to determine the magnification factor on the CCD [1].
The hybrid compact gamma camera (figure 2), combines gamma and optical cameras, this offers optical, gamma and fused imaging. Tungsten shielding of 3 mm thickness surrounds the head of the hybrid camera and, in order to isolate the head thermally and electrically, it is sealed in a non-toxic plastic enclosure. Both the gamma-ray and optical cameras are connected to the readout and control electronic system and all are managed by a standard PC or laptop [3].
Results and discussions
The performance of the HCGC was characterised successfully. The results agreed that it has spatial resolution of less than 1mm with system sensitivity of up to 214cps/MBq. Fused images showed good alignment of the two modalities allowing good localization of activity.
Conclusion
The efficacy of a hybrid camera has been described and initial images demonstrate that it is ideally suited for intraoperative imaging. The anatomy and structural appearance detected by the optical camera aids the physical localization of radiopharmaceutical uptake. Based on these studies, further evaluation of the hybrid camera could be carried out to be prepared for its use in a surgical theatre setting.
References
1. Lees, J.E., D.J. Bassford, O.E. Blake, P.E. Blackshaw, and A.C. Perkins, A high resolution Small Field Of View (SFOV) gamma camera: a columnar scintillator coated CCD imager for medical applications. Journal of Instrumentation, 2011. 6(12): p. C12033-C12033.
2. Bugby, S.L., J.E. Lees, B.S. Bhatia, and A.C. Perkins, Characterisation of a high resolution small field of view portable gamma camera. Phys Med, 2014. 30(3): p. 331-9.
3. Lees, J.E., S.L. Bugby, B.S. Bhatia, L.K. Jambi, M.S. Alqahtani, W.R. McKnight, A.H. Ng, and A.C. Perkins, A small field of view camera for hybrid gamma and optical imaging. Journal of Instrumentation, 2014. 9(12): p. C12020-C12020.
| المرفق | الحجم |
|---|---|
| 1.33 ميغابايت |
