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Mansour I. Almansour منصور إبراهيم محمد المنصور

Professor

عضو هيئة تدريس

كلية العلوم
Building 5, , Office No. 60 B | Phone: 01146759221ب 60 مبنى 5 كلية العلوم
المنشورات
مقال فى مجلة
2015

Morphometric Alterations Induced by the Toxicity of Variable Sizes of Silver Nanoparticles

Silver nanoprticles (SNPs) are invested in medical, industrial and environmental applications. Little if any, is known about the morphometric alterations induced by the toxicity of SNPs. The aim of the present work is to find out the effect of variable size of SNPs on different morphometric parameters. Adult healthy male mice (BAL/C) were subjected to (10 nm, 20 nm, 40 nm 60 nm and 100 nm) SNPs for 35 days. Silver NPs caused non-significant decline on the average weight, significant decline in food consumption, increase in water intake, unilateral blindness, tanning fur color and cholestasis together with a decrease in the relative ratio of the liver, kidney and spleen weight to body weight. Mice subjected to 10 nm and 20 nm were more affected than mice receiving larger nanoparticles. These findings may indicate that SNPs could induce morphometric alterations that are size related wheresmaller SNPs have more impact than the larger ones.

 

مزيد من المنشورات
publications

Abstract: Tubulin is still a highly valued target in cancer chemotherapy. Agents that target tubulin
and microtubule dynamic are considered to be of high therapeutic potential. We conducted…

بواسطة Aisha Alqarni1,*, Yasser A. Elnakady1 , Lamya Alsadhan 1 , Muhammad Abbas2 , Wolfgang Richter2 , Badr A. Aldahmash1 , Mansour I. Almansour1 , Layali M. Almutairi1 and Ahmed Rady1
2023
publications

Silver nanoparticles (SNPs) are widely used in nanomedicine and consuming products with potential risk on human health.

2016
publications

:MalealbinoWistarratswereexposedto10nmgoldnanoparticlesatadoseof2000µg/kgtogetherwithor withoutpropolis(50mg/kg)for15consecutivedays. Freshrenalbiopsiesfromofallinvestigatedratswerecutrapidly,…

2016