المنشورات و المؤلفات
According to literature, ibrutinib (IBR) is a practically insoluble drug in water. The practically insoluble nature of
IBR creates several problems in dosage form design of IBR. Hence, in thiswork, the thermodynamics of solubility
of IBR in various...
Quetiapine is an atypical antipsychotic, used clinically in the treatment of schizophrenia, acute mania in bipolar disorders, and bipolar depression in adults. In this study, the effect of green tea extracts (GTE) on the pharmacokinetics of...
In the present study, various nanoemulsion formulations of carvone Schiff base of isoniazid (CSB-INH) were
developed by aqueous phase titration method in order to evaluate its anticancer potential. Developed
nanoemulsions of CSB-INH were...
Ibrutinib is a recently approved anticancer drug recommended for the treatment of mantle cell lymphoma
and chronic lymphocytic leukemia. It has been reported as practically insoluble in water and
hence it is available in the market at higher doses....
Vilazodone is a novel antidepressant agent, approved by the US Food
and Drug Administration (US FDA) for the treatment of major depressive
disorder. In this study, a fast sensitive ultra-high performance liquid
chromatography–tandem mass...
tIn this study, a sensitive UPLC–MS/MS assay was developed and validated for high-throughput determi-nation of pomalidomide in rat plasma using celecoxib as an internal standard (IS). Liquid liquid extractionusing dichloromethane was employed to...
Canagliflozin is the first sodium-glucose co-transporter-2 inhibitor, approved by the US Food and Drug Administration for the treatment of type 2 diabetes mellitus. In this study, a sensitive UHPLC-MS/MS assay for rapid determination of...
Canagliflozin is the first sodium–glucose co-transporter-2 inhibitor approved for the treatment of type 2
diabetes mellitus. In this study, a simple and sensitive HPLC assay with a florescence detector was
developed for accurate quantification of...
A simple and sensitive UPLC–MS/MS assay was developed and validated for rapid determination of
thiosemicarbazide derivative of isoniazid (TSC-INH), a potent anti-candidal agent in rat plasma, tissues,
urine and feces. All biological samples were...