مساعد بن علي الحدب الشمري
دكتوراة في علم الأدوية العصبية، مهتم بأبحاث الأمراض العصبية والنفسية
Musaad Ali Alshammari
PhD. in Neuropharmacology , Interested in Cellular & Molecular Neurobiology and Neuroelectrophysiology of Psychiatric Disorders
RESEARCH INTERESTS
Identify the best therapeutic intervention for neurological and psychiatric disorders using translational approaches including, genetically and pharmacologically diseased-based animal models.
My goals
Understand the biology of pathological dysfunctions in brain disorders such as depression, autism, anxiety, pain, and attention deficit hyperactivity disorder (ADHD), schizophrenia, Alzheimer, and epilepsy.
Identify a biological link between CNS disorders and metabolic diseases such as diabetes and obesity.
Characterize signaling pathways critically involved in brain disorders.
Identify a potential biomarker and drug target / examine these drug targets.
Area of Research
Currently, my work centers on understanding the role of the molecular mechanisms underlying adult neural stem cells development in the adult mammalian brain. I am interested in identifying a novel regulator of adult neurogenesis that may be the key molecule in the pathogenesis of major neuropsychiatric disorders.
Cognitive processes require gamma-amino-butyric acid (GABA) interneurons. Via complex synaptic connections, these cells regulate cellular excitability and synaptic plasticity of principal...
Genetically inherited mutations in the fibroblast growth factor 14 (FGF14) gene lead to spinocerebellar ataxia type 27 (SCA27), an autosomal dominant disorder characterized by heterogeneous...
Cognitive processing is highly dependent on the functional integrity of gamma-amino-butyric acid (GABA) interneurons in the brain. These cells regulate excitability and synaptic plasticity...