Investigation of a novel small field of view hybrid compact gamma camera (HCGC) for scintigraphic imaging

Conference Paper

alqahtani, M.S. . 2016

• نوع عمل المنشور: electronic poster
• رابط المنشور على الويب: http://dx.doi.org/10.1594/ecr2016/B-0033
• اسم المؤتمر: ECR European Congress of Radiology 2016
• عنوان المؤتمر: Vienna
• تاريخ المؤتمر: الأربعاء, آذار (مارس) 2, 2016
• المنظمة الراعية: European Society of Radiology

مستخلص المنشور

Purpose
 The Hybrid Compact Gamma Camera (HCGC) has been developed to provide additional localisation information during procedures such as sentinel lymph node (SLN) biopsies. In this study, a lymph-node contrast (LNC) phantom and an evaluative technique that involved idealised medical scenarios were modelled to study the HCGC detectability of varying radioactivity concentration and sentinel lymph node size.
 
Materials and Methods
The LNC phantom is made of Perspex plates, with simulated SLNs of diameters ranging between 10 and 2.5mm (16 SLNs in total). These simulated SLNs are positioned beneath thicknesses of scattering material ranging between 5mm and 40mm. The LNC phantom has four different background wells to simulate activity uptake surrounding the SLNs. The simulated activities ranged between 4MBq and 0.025MBq for the SLNs following their sizes. The simulated background activity was 1/10 of the simulated activity in the SLN.
 
Results
Spatial resolution measurements and Signal to Noise Ratio (SNR) analysis of the SLN were used as the main criteria to compare imaging sets produced by the HCGC with acquisition times ranging between 60 and 240s. The HCGC can successfully detect 87.5% to 100% (depending on the acquisition time) and 75% to 93.75% of the SLNs that are positioned underneath 20 and 40mm thicknesses of Perspex respectively. The HCGC provides good spatial resolution images for detected SLNs ranging between 9.5 and 12mm.
 
Conclusion
The evaluation of the HCGC in this study shows that it is well suited for SLN imaging. The HCGC capability to detect low activity uptake in a small SLN indicates its usefulness as an intraoperative imaging system during critical surgical SLN procedures.