Q-Banding

Book Chapter

Amor, Nabil . 2017

• نوع عمل المنشور: PostDoc
• رابط المنشور على الويب: Reference Module in Life Sciences (LIFE): Q-Banding
• الوسوم: Q-Banding, Karyology, Human, Animal
• اسم الجهة الناشرة: Elsevier Inc.

مستخلص المنشور

 
Since the introduction of quinacrine mustard as a banding agent, it was a revolution on cytogenetics. Fluorochrome banding technique

using quinacrine produces a yellow fluorescence of differing intensity (Q-bands). Q-banding was first developed for plant

chromosomes and was later successfully extended to human chromosomes and then to other animal systems, with modifications.

Q-banding has been successful not only in establishing standard human karyotype but also in ascribing structural    chromosome

rearrangements, such as duplications/deletions, peri- and paracentric inversions, and aneuploidy (chromosome monosmy or trisomy).