Synthesis, Spectroscopic Investigations (X-ray, NMR and TD-DFT), Antimicrobial Activity and Molecular Docking of 2,6-Bis(hydroxy(phenyl)methyl)cyclohexanone

Journal Article

, Assem Barakat, Hazem A. Ghabbour, Abdullah Mohammed Al-Majid, Saied M. Soliman, M. Ali, Yahia Nasser Mabkhot, Mohammed Rafi Shaik and Hoong-Kun Fun . 2015

• رابط المنشور على الويب: Synthesis, Spectroscopic Investigations (X-ray, NMR and TD-DFT), Antimicrobial Activity and Molecular Docking of 2,6-Bis(hydroxy
• المجلة \ الصحيفة: Molecules
• رقم العدد: 7
• رقم الإصدار السنوي: 20
• الصفحات: 13240-13263

مستخلص المنشور

The synthesis of 2,6-bis(hydroxy(phenyl)methyl)cyclohexanone 1 is described. The molecular structure of the title compound 1 was confirmed by NMR, FT-IR, MS, CHN microanalysis, and X-ray crystallography. The molecular structure was also investigated by a set of computational studies and found to be in good agreement with the experimental data obtained from the various spectrophotometric techniques. The antimicrobial activity and molecular docking of the synthesized compound was investigated.