313 PHL - 315 PHL

Pharmacology - I:

Course description:
This course is an  introduction to the basic principles of pharmacology and the pharmacological actions, therapeutic uses, mechanisms of action, adverse effects, contraindications and drug interaction of autonomic drugs, cardiovascular drugs, diuretics, and autocoids.

practical work objectives:
To learn about some in-vitro experiments demonstrating the effects of autonomic drugs, cardiovascular drugs, diuretics, and autocoids.
practical work :

• Introduction and dose response curve of different doses of acetylcholine.
• Effects and site of action of different agonist drugs on the isolated rabbit intestine.
• Effects of certain agonists and their antagonists on the isolated rabbit intestine.
• Effects of certain agonists and their antagonists on the isolated guinea pig ileum.
• Dose response curve of acetylcholine and the effect of different drugs on isolated frog rectus abdominis.
• Effect of different drugs on the blood pressure of anaesthetized rabbit.
• Effect & site of action of different drugs on isolated rabbit's heart (Langendorff preparation).

In addition to the tutorial sections (group presentation) done by the students in different topics including:

• G-proteins, ion channels, adrenergic and cholinergic receptors, cotransmission, skeletal muscle relaxant, pharmaceutical forms, and glaucoma.

References:

• Rang & Dale's Pharmacology By Humphrey P. Rang, Maureen M. Dale, James M. Ritter, Rod J. Flower.  Latest edition.
• Bertram G. Katzung Basic and Clinical Pharmacology. Latest edition.

Marks:                                    
Total       20