White mold, caused by Sclerotinia sclerotiorum (Lib.) de Bary, is the most globally significant disease of Jerusalem Artichoke (JA) causing considerable losses during storage periods. The aim of this study was to evaluate the use of a natural essential oil for control of white mold disease, sprouting suppression and quality maintaining of JA tubers under storage periods. In vitro fungitoxicity was investigated using two natural essential oils; clove and sweet wormwood at concentrations of (2, 3, 4 and 5%). Clove oil at 2% inhibited completely the fungal growth of S. sclerotiorum.