Objectives: To evaluate the impact of routine open mouth osseous TMJ tomography on diagnosis and treatment planning of TMJ conditions. Investigating the need for such images is important in order to justify the additional radiation exposure imparted by such images.
Although a number of chemicals have been isolated from Strychnos nux-vomica, only a few have been evaluated for their biological significance. As a part of our drug discovery programme for cytotoxic agents from Indian medicinal plants, a novel cytotoxic agent, loganin (1) was isolated from the fruit pulp of S. nux-vomica. The loganin (1) showed significant anticancer activity against the human liver (WRL-68), colon (COLO-320 and CaCo2), ovarian (PA-1) and breast (MCF-7) cancer cell lines.