Various antecedents support the adoption of organizational innovation. Despite the extensive research on innovations, research focusing on how these antecedents affect psychological empowerment has remained thin. The objective of this study was to investigate the impact of six antecedents supporting organizational innovation (employee participation, training and development, organizational culture, incentives, leadership pattern, and teamwork) on the four constructs of psychological empowerment (meaningfulness, competence, self-determination, and impact).