The bioactive compounds proceraside A, frugoside and calotropin, which were extracted from the root bark of Calotropis procera (Aiton) W.T. Aiton (family Asclepiadaceae), were recently reported to inhibit the growth of inhibition against various human cancer cell lines in vitro. However, their modes of action have not been clearly defined. Therefore, we attempted an in silico approach to gain insights into their binding modes against the following selected molecular targets: CDK-2, CDK-6, topoisomerase I, BCL-2, VEGFR-2, telomere: G-quadruplex, and topoisomerase II.

Growing concerns about the economical feasibility of materials synthesis means that simple methodologies
to furnish materials are needed. Moreover, the multi-functional activity of these as-prepared materials is of
great importance. Hence, here we report nitrogen-doped carbon nanoparticles from a one-step flame
synthesis by directly burning pyrrole at room temperature and in an air atmosphere. The as-synthesized
N-doped carbon was scrutinized as a cathode material for the oxygen reduction reaction and was also

The taxonomic status of Euryops jaberiana Abedin & Chaudhary (tribe
Senecioneae, family Asteraceae), endemic to northern Saudi Arabia was evaluated based
on molecular phylogenetic analyses of internal transcribed spacer sequence (ITS) of
nuclear ribosomal DNA (nrDNA) in order to ascertain its position within the genus. The
phylogenetic tree constructed by the Neighbour Joining, Maximum Parsimony and
Maximum Likelihood analyses showed a clear resolution of taxon included in the

Silver nanoparticles (AgNPs) are an important class of nanomaterial used for a wide range of industrial and biomedical applications. Adenium obesum is a plant of the family Apocynaceae that is rich in toxic cardiac glycosides; however, there is scarce information on the anticancer potential of its AgNPs. We herein report the novel biosynthesis of AgNPs using aqueous leaf extract of A. obesum (AOAgNPs). The synthesis of AOAgNPs was monitored by color change and ultraviolet–visible spectroscopy (425 nm).