Abstract: This study was to compare the efficacy of continuous, bi-level positive airway pressure (CPAP, Bi-PAP) and

oxygen therapy on detailed observation of time-course change in blood gases, physiological parameters and rate of

endotracheal intubation in patient with acute cardiogenic pulmonary edema (ACPE). Sixty-six patients with ACPE were

randomly assigned to receive standard oxygen (O2) therapy (n=23), CPAP (n=21), and Bi-PAP (n=22). Blood gases (PaCO2,