Targeted nano-delivery of novel omega-3 conjugate against hepatocellular carcinoma: Regulating COX-2/bcl-2 expression in an animal model

The present approach enumerates the effectiveness of tuftsin tagged nano-liposome for the cytosolic
transport of 2,6-di-isopropylphenol-linolenic acid conjugate against liver cancer in mice. Initially, the
conjugate in its free form was examined for anticancer potential on HepG2 liver cancer cells. Induction of
apoptosis and suppression of migration and adhesion of HepG2 cells confirmed the effectiveness of
conjugate as an anticancer agent. After this, role of the conjugate entrapped in a nano-carrier was

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