Envisaging the role of Co in theranautics and biomedicine it is immensely important to evaluate its anti-microbial activity. Hence in this study CoO thin nanosheets (CoO-TNs) were synthesized using wet chemical solution method at a very low refluxing temperature (90 o C) and short time (60 min). Scanning electron microscopy of the grown structure revealed microflowers (2~3 µm) composed of thin sheets petals (60~80 nm). The thickness of each individual grown sheet varies from 10~20 nm.

Recently, nanoscale (<100 nm) inorganic materials, especially spherical shaped zinc oxide (ZnO-QDs) have received significant attention from broad community because of their potential utalizations in various technologies. Due to their large surface to volume (S/V) ratio contributions and extremely high reactivities, they can easily penetrate in various biological identities, like cells, proteins and hence can sense, diagnose and cure different biological systems.

We have evaluated the in vitro low dose hepatotoxic effects of two flame-retardants (BDE-47 and BDE-32) in HepG2 cells. Both congeners declined the viability of cells in MTT and NRU cell viability assays. Higher level of intracellular reactive oxygen species (ROS) and dysfunction of mitochondrial membrane potential (ΔΨm) were observed in the treated cells. Comet assay data confirmed the DNA damaging potential of both congeners. BDE-47 exposure results in the appearance of subG1 apoptotic peak (30.1%) at 100 nM, while BDE-32 arrested the cells in G2/M phase.

Copper ferrite nanoparticles (NPs) have the potential to be applied in biomedical fields such as cell labeling and hyper-

Envisaging the role of Co in theranautics and biomedicine it is immensely important to evaluate its anti- microbial activity. Hence in this study CoO thin nanosheets (CoO-TNs) were synthesized using wet chemical solution method at a very low refluxing temperature (90 oC) and short time (60 min). Scanning electron microscopy of the grown structure revealed microflowers (2~3 μm) composed of thin sheets petals (60~80 nm). The thickness of each individual grown sheet varies from 10~20 nm.

Dexrazoxane is the only clinically approved cardioprotectant against anthracyclines-induced cardiotoxicity. Thus, detailed evaluation of the genotoxic potential of dexrazoxane and anthracyclines combination is essential to provide more insights into genotoxic and anti-genotoxic alterations that may play a role in the development of the secondary malignancies after treatment with anthracyclines.

Oral cavity is inhabited by more than 25,000 different bacterial phylotypes; some of them cause systemic infections in addition to dental and periodontal diseases. Emergence of multiple antibiotic resistance among these bacteria necessitates the development of alternative antimicrobial agents that are safe, stable, and relatively economic. This review focuses on the significance of metal oxide nanoparticles, especially zinc oxide and titanium dioxide nanoparticles as supplementary antimicrobials for controlling oral infections and biofilm formation.

Copper ferrite nanoparticles (NPs) have the potential to be applied in biomedical fields such as cell labeling and hyperthermia. However, there is a lack of information concerning the toxicity of copper ferrite NPs. We explored the cytotoxic potential of copper ferrite NPs in human lung (A549) and liver (HepG2) cells. Copper ferrite NPs were crystalline and almost spherically shaped with an average diameter of 35 nm.