The optimized molecular structure, vibrational wavenumbers, corresponding vibrational assignments of
2-[4-(4-phenylbutanamido)phenyl]-5-ethylsulphonyl-benzoxazole have been investigated experimentally and
theoretically using Gaussian09 software. The wavenumbers were assigned by potential energy distribution
and the frontier molecular orbital analysis is used to determine the charge transfer within the molecule. The
stability of the molecule arising from hyper-conjugative interaction and charge delocalization has been analyzed

Background: The quinazoline are an important class of medicinal compounds that possess a number of biological
activities like anticancer, anticonvulsant and antioxidant etc.
Results: We evaluated the previously synthesized quinazoline derivatives 1–3 for their anticancer activities against
three cancer cell lines (HepG2, MCF-7, and HCT-116). Among the tested compounds, quinazolines 1 and 3 were
found to be more potent than the standard drug Vinblastine against HepG2 and MCF-7 cell lines. All the tested compounds

Novel series of 4,6-disubstituted-1,3,5-triazines containing hydrazone derivativeswere synthesized employing ultrasonic irradiation and conventional heating.The ultrasonication gave the target products in higher yields and purity in shorter reaction time compared with the conventional method. IR, NMR (1H and 13C), elemental analysis, and LC-MS confirmed the structures of the new products.The antimicrobial and antifungal activities were evaluated for all the prepared compounds against some selected Grampositive and Gram-negative bacterial strains.

The FT-IR and FT-Raman spectra of 5-chloro-N-(2-chlorophenyl)pyrazine-2-carboxamide were recorded and the vibrational wavenumbers are computed using DFT method. On the basis of potential energy distribution the complete vibrational assignments were performed. From the molecular electrostatic potential study the negative potential regions are mainly localized over the carbonyl group and phenyl ring and are possible sites for electrophilic attack. The calculated HOMO and LUMO energies confirm that charge transfer occurs within the molecule.

The prepared 4-chloro-3-methylphenyl quinoline-2-carboxylate has been investigated by both experimental and theoretical

This current review focuses on ultrasound irradiation literature published between 2008– 2015 and is a continuation of the previous published work2 which also reviewed the literature published from 1980–2007. This review revives the effect of ultrasound on the development of chemical reaction and to highlight some applications of sonochemistry in various organic synthesis such as alkylation, condensation and cycloaddition.