Psoriatic inflammation has been shown to be associated with cardiovascular dysfunction and systemic inflammation. Recently, psoriasis has also been linked to hepatic disorders, however underlying mechanism connecting the two are unknown. IL-17A being a central pro-inflammatory cytokine in the pathogenesis of psoriasis may be involved in hepatic inflammation through its receptor and downward signaling; however so far no study has investigated IL-17A related signaling in the liver during psoriasis in a murine model.
This study was designed to characterize the DNA polymorphisms of the melanocortin-1 receptor (MC1R) gene in indigenous Saudi Arabian sheep breeds exhibiting different color coats, along with individuals of the Sawaknee breed, an exotic sheep imported from Sudan.
The course will cover the techniques and clinical uses of the various massage manipulation through practical demonstration and practice sessions. Attention of the students will be drawn to the specific clinical application of each massage manipulation, the physiological and therapeutic effects, as well as their dangers and contraindication. Teaching and learning in this course will be through practice on human models in the laboratory.