Diazinon is a widely used organophosphorus pesticide in agriculture and environmental health ,
hence its adverse effects on non target animals, especially on fish is to be determined. The present research is
conducted to study the influence of diazinon [0, 0-diethyl 0-(2-isopropyl-6-methylpyrimidin-4yl) phosphorothioate]
on acetylcholinestrase (AChE) and lipidperoxidation (LPO) on freshwater common carp (Cyprinus carpio L.). Adult
fish (mean body weight 42.6±3.86 g and 19.1±2.66 cm mean length ) were divided into five groups with 3 replicates

The objective of this study was to evaluate the effect of commercial formulation of triazophos on
esterase activity in the liver, kidney, brain, blood and muscles of Catla catla, Labeo rohita and
Cirrhinus mrigala fingerlings. Toxicity of triazophos was tested in the fingerlings of major carps
following static bioassay and probit analysis. The fingerlings of C. catla, L. rohita and C. mrigala
were exposed to three sub lethal concentrations: 1/5th (0.97, 0.48, 0.32), 1/10th (1.33, 0.66, 0.44) and

Effects of inorganic mercury have been studied on the drug metabolizing enzymes (DME) of
phenobarbitone- (PB-) and promethazine- (PM-) pretreated male New Zealand white rabbit,
Oryctolagus cunciculus. After PB treatment, the activities of cytochrome p-450 (CP), aniline
hydroxylase (AH), acetanilide hydroxylase (AAH), benzphatamine demethylase (BD), aminopyrine
demethylase (APD) and N.N dimethyl aniline demethylase (DAD) increased 214, 266, 207, 108, 81
and 83%, respectively. Cytochrome-c-reductase (CCR) also increased 109%. However, the activities

The aquatic environment of the Red Sea is facing many threats resulting from land-based activities.
The aim of the present study was to measure the concentrations of polycyclic aromatic hydrocarbons
(PAHs) in Red Sea shrimp and to assess the health risk resulting from their consumption.
Gas chromatography/flame ionization detection was used for PAH detection.
Polycyclic aromatic hydrocarbons exceeded the maximum residue levels authorized in crustaceans.
They were found to be of pyrogenic source, and their total toxicity equivalent concentration was

Industrialization and anthropogenic activities are constantly introducing heavy metals in biosphere,
which is becoming a serious global issue. Arsenic and cadmium are known human carcinogens, while exposure of
lead is also very toxic for human body. In the present study, anti-proliferative effects of arsenic, cadmium and lead
were investigated on rat pups brain cells (RPBCs). RPBCs were isolated from one day old rat pup after dissection of
brain. Anti-proliferative effects of arsenic, cadmium and lead were tested by neutral red uptake assay. Both arsenic

Histopathological changes have been recorded in the gills, liver and intestinal tissue of Labeo rohita
from River Ravi receiving industrial waste. Varying concentrations of Pb and Cu were recorded in
the liver, gills and intestine of Labeo rohita. The pronounced histopathological changes like
degeneration, necrosis and disorganization of lamellae and hyperplasia of epithelial cells was
observed in the gills of the fish collected from a polluted site as compared to the fish from a control