The use of synthetic organic pesticides has serious economic, social and environmental ramifications. Thus, this study describes the experiments using botanical and bacterial extracts to control the samsum ant (Pachycondyla sennaarensis). This ant is widely distributed in many parts of southern Saudi Arabia, and has been established as a household pest ant. Three Saudi plants, harmal (Rhaza stricta), boxthorn (Lycium shawii) and artemisia (Artemisia inculta) and two bacterial extracts, Pseudomonas frederiksbergensis and Streptomyces sp.