The objective of this study was to look at the pattern of serum total cholesterol concentration (TCC) distribution and the prevalence of hypercholesterolemia (HC) in Saudi Arabia. A cross-sectional national epidemiological household survey was carried out, consisting of 4539 Saudi subjects, over the age of 15 years. The sample was adjusted for gender, age, regional and residency, and urban versus rural population distribution. The following details were taken for each subject: height, weight, calculation of body mass index (BMI) and random blood samples for total cholesterol measurements.