Plant species Rhazya stricta, which naturally grown around Mahad AD’Dahab Mine, have been selected to study its ability to accumulate heavy metals (Cd, Cu, Pb, Zn). Twenty four samples from roots, stems, and leaves of Rhazya stricta were collected at 0, 1, 2, 3, 4, 5, 6, and 7 km far from the landfill. Moreover, eight soil samples compost were collected from each site to collect plant samples. Plant and soil samples were analyzed for total concentration of Cd, Cu, Pb, and Zn. Results showed soil contamination with respect to Cd, Cu, Pb and Zn.