A Bioinformatics Approach for In Vivo Imaging of Endogenous MicroRNA Targets During Neurogenesis

MicroRNAs (miRNAs), a class of small non-coding RNAs, have been reported to be functionally

involved with cellular metabolism and a variety of diseases. The importance of miRNA expression and functional

targeting has recently become a focus of intense research. However, their endogenous molecular targets have not

been clearly identified despite multiple attempts in prior studies using bioinformatics. Our bioinformatics strategy

and in vitro validation by the PCR, identified 16 out of 337 miR124a-predicted targets and 5 out of 299 miR9*-predicted

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اشترك ب KSU Faculty آر.إس.إس