Multimodal imaging systems may eliminate the disadvantages of individual imaging modality by
providing complementary information about cellular and molecular activites. In this sutdy, we developed
a reverse complementary multimodal imaging system to image microRNAs (miRNA, miR) during neurognesis
using transferrin receptor (TfR) and a magnetic fluorescence (MF) nanoparticle-conjugated
peptide targeting TfR (MF targeting TfR). Both in vitro and in vivo imaging demonstrated that, in the