An experiment was carried out, firstly, to determine the possible toxicity of Carum copticum (Apiaceae)
extract against Culex pipiens (Diptera: Culicidae), and, secondly, to study the histopathological alterations
in the midgut of Cx. pipiens as a result of treatment with C. copticum extract. Larvicidal and ovicidal activities
of C. copticum extract against the larvae of Cx. pipiens was determined according to World health
organization (WHO). The inhibition effect of C. copticum was assessed by determining the mortality of

Background: The incidence of mosquito-borne diseases and the resistance of mosquitoes to conventional pesticides
have recently caused a panic to the authorities in the endemic countries. This study was conducted to identify native
larvicidal biopesticides against Culex pipiens for utilization in the battle against mosquito-borne diseases.
Methods: Larvicidal activities of new indigenous Bacillus thuringiensis isolates and crude toxin complexes (TCs) of
the two nematode bacterial-symbionts, Photorhabdus luminescens akhurstii (HRM1) and Ph. luminescens akhurstii

Background: The incidence of mosquito-borne diseases and the resistance of mosquitoes to conventional pesticides
have recently caused a panic to the authorities in the endemic countries. This study was conducted to identify native
larvicidal biopesticides against Culex pipiens for utilization in the battle against mosquito-borne diseases.
Methods: Larvicidal activities of new indigenous Bacillus thuringiensis isolates and crude toxin complexes (TCs) of
the two nematode bacterial-symbionts, Photorhabdus luminescens akhurstii (HRM1) and Ph. luminescens akhurstii