Chronic low-grade inflammation is a significant factor in the development of obesity associated diabetes. This is supported by recent studies suggesting that endotoxin, derived from gut flora, may be key to the development of inflammarion by stimulating the secretion of an adverse cytokine profile from adipose tissue. The study investigated the relationship of endotoxin on several metabolic parameters of diabetic patients.

BACKGROUND:

This study aims to identify which among the metabolic syndrome (MS) definitions are closely associated with pathological levels of leptin, adiponectin, resistin, tumour necrosis alpha (TNF-alpha) and C-reactive protein (CRP) among type 2 diabetics.

MATERIALS AND METHODS:

Abstract: The aim of the study was to determine surgical indication and complication of subtotal thyroidectomy in patients being treated for Graves’ disease at King Khalid University Hospital Riyadh Saudi Arabia in the period between January 1996 and December 2005. Twenty-five out of 194 adult patients with Graves’ disease had thyroidectomy for hyperthyroidism during the 10-year period representing 13% comprising 11 males and 14 females. Mean age at presentation for all the patients was 28±12 years.

BACKGROUND:

OBJECTIVE:

To determine whether clinical and biochemical features of Graves' disease at presentation predict response to medical and radioiodine treatment.

METHODS:

We carried out a retrospective 10-year study of 194 consecutive Saudi subjects with Graves' disease who were treated with antithyroid drugs, radioiodine therapy, or both, between January 1995 and December 2004 at King Khalid University Hospital, Riyadh, Saudi Arabia.

RESULTS: