Effect of care solutions on contact lens in-vivo wettability at insertion and end of day
Manahilov, Alan Tomlinson, Raied Fagehi, Velitchko . 2013
Purpose:To investigate the wetting of a soft contact lens (SCL) after storage in various multipurpose solutions (MPS) (compared to wetting with the pack solution), to assess the sustained benefits after 8 hours of wear.
Methods:Ten SCL wearers (age range 26.6± 6.3 yrs) were included in this study. A Doane interferometer captured images of the pre-lens tear film on a single type of SCL, ACUVUE OASYS (Johnson & Johnson). The SCL wettability was measured after storage in the pack solution or one of five MPS: Opti-Free EverMoist and Express (Alcon), COMPLETE MPS (AMO), ReNu and Biotrue (Bausch & Lomb). The wettability was measured after 15 min (time A) and 8 hours (time B) of wear of the lens by each subject. Four previously described parameters of wettability were assessed: onset latency (OL), the time to first break-up; drying duration (DD), the duration of drying after first break-up; the maximum speed of drying (MS); and the time to reach this maximum speed (PL).* The OSDI questionnaire was completed by the subjects, at each visit, to evaluate the subjective response to the solutions.
Results:There was no significant difference between CL wetting measured after storage in the MPS compared to the pack solution for all four wetting variables (Friedman test, P>0.05). However, storage of the lens in some MPSs showed more sustained wetting after 8 hours wear, with similar values at (A) and (B); for OL, ReNu and Complete; for DD and MS Biotrue, Express and Complete; and for PL ReNu, Express and Complete. The OSDI questionnaire showed less discomfort after 8 hours wear (at B) with storage in all the MPSs compared to the pack solution (p< 0.02).
Conclusions:The effect of all MPS on the initial wetting of a SCL (compared to that with the pack solution) was limited. However, the ability to sustain wetting of a SCL over 8 hours of wear was better with Biotrue, Opti-Free Express and Complete. The wetting parameter of drying duration gave the closest objective measure to subjective responses to lens wear (Figure 1and 2). *Fagehi R, Tomlinson A, Manahilov V. ARVO 2011 E-abstract: 6524, 2011.
Purpose:To investigate the wetting of a soft contact lens (SCL) after storage in various multipurpose solutions (MPS) (compared to wetting with the pack solution…