Saleh Ali Al-Obeidan

Saleh Al-Obeidan, MD
Department of Ophthalmology
King Abdul Aziz University Hospital
Riyadh, Kingdom of Saudi Arabia 
P.O. Box 245 Riyadh 11411

Contact No:+966 11 4775723
E-mail Address:     alobeidan@yahoo.com; salobeidan@ksu.edu.sa

Educational & Postgraduate Training

                                            Riyadh, Saudi Arabia
                

                                            Cairo, Egypt
 

                                            Over-all evaluation – Excellent
                                            King Saud University Hospital & Riyadh Central Hospital
                                            Riyadh, Saudi Arabia
                                                                       

                                            Joint Venture of King Saud University & King Khaled Eye Specialist Hospital
                                            Riyadh, Saudi Arabia
                                

                                            Riyadh, Saudi Arabia
 

Appointments:

                                            Glaucoma and Anterior Segment Divisions
                                            King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia
 

                                            King Saud University, Riyadh, Saudi Arabia
 

                                            King Khaled University Hospital,
                                            King Saud University, Riyadh, Saudi Arabia
 

                                            Department of Ophthalmology
                                            King Saud University, Riyadh, Saudi Arabia
 

                                            Department of Ophthalmology,
                                            King Saud University, Riyadh, Saudi Arabia
 

                                            Department of Ophthalmology,
                                            King Saud University, Riyadh, Saudi Arabia
 

                                            European Society of Cataract and Refractive Surgeons
 

                                            Saudi Board of Ophthalmology
 

                                            King Faisal University Fellowship in Ophthalmology
 

                                            Department of Ophthalmology, College of Medicine,
                                            King Saud University, Riyadh Saudi Arabia
 

                                            Glaucoma Research Chair
                                            College of Medicine, King Saud University
                                

                                            Department of Ophthalmology,
                                            King Saud University, Riyadh
 
  
Research:

• Co-author in Retrospective Study on Malignant Glaucoma at KKESH (on going).
• Co-author in a Retrospective Study on Trans-Scleral Yag Cyclophotocoagulation Experience at KKESH. Completed and Published in Ophthalmic Surgery, August 1993.
• Literature review on Ghost-cell-Glaucoma. Accepted by the Department of Ophthalmology, KSU as thesis for the following year 1990.
• Co-author in Retrospective Study on Management of Leaking Filtration Bleb.
• Single Author in Misdiagnosis of the Spasm of the Near Reflex. Published in Saudi Journal of Ophthalmology, Spring Issue.
• Co-author Pars Plana Vitrectomy for Ghost Cell Glaucoma. Published in Eye International, 1995.
• Co-author in Post-traumatic Endophthalmitis: causative organisms and visual outcome Published in European Journal of Ophthalmology, Vol.9 n.1 1999
• Co-author in the effect of topical medication and pre-existing ocular disease on conjunctival cellular profile and reactivation – correlation of histology with filtration surgery.

Meetings Attended:

• ​Most of the Saudi Ophthalmology Meetings since 1991 till 2008.
• 6th International Glaucoma Symposium, Athena (March 28 – 29, 2007)
• Invited Speaker in Glaucoma Meeting, Basel, Switzerland (Oct. 18 – 19, 2008)
• 5th International Congress on Glaucoma Surgery, New Delhi, India (November 11-13, 2010)
• World Glaucoma Congress, Paris (June 29 – July 02, 2011)
• Kuwait Ophthalmological Society Conference, Kuwait (September 29 – October 01, 2011)
• World Ophthalmology Congress, Abu Dhabi (February 16 -20, 2012)
• International Congress Glaucoma Surgery, Glasgow, UK (September 11-17, 2012)
• American Academy of Ophthalmology, Chicago, USA (November 9-14, 2012)
• 9th International Symposium of Ophthalmology (ISO) - Guangzhou, China (November 9-11, 2013)
• 6th World Glaucoma Congress, Hong Kong (June 06– 09 2015) 
• 1st Nourseen Glaucoma Symposium, Cairo, Egypt (July 31 – August 2, 2015)
• 33rd Congress of the ESCRS, Barcelona, Spain (September 5 – 9, 2015)
• Al Qassimi Ophthalmology International Conference, Dubai, UAE (October  8-10, 2015)

  
Awards:         

• Best Resident      1988
• Best Resident      1990
• Best Teacher       for the academic year 2005 - 2006
• Best Teacher       for the academic year 2006 - 2007
• Best Teacher       for the academic year 2009 – 2010

 
Patency:

 
 
Community Services:
 

 
  
Research Chair Events:

• TV & Radio interviews and Magazine Publications
• Announcement in Riyadh Magazine: The first operation in the Middle East on “Canaloplasty for Open Angle Glaucoma” (November 9, 2010)
• Signing of agreement between King Saud University and Bascom Palmer Institute, Miami, Florida (April 11, 2012)

 
 
Clinical Trials Conducted:

 
 
International Publications:

1. Incidence and Risk Factors for Developing Glaucoma Among Patients with Uveitis in a University-based Tertiary Referral Center in Riyadh, Saudi Arabia.  Al Rubaie K, Al Dhahri H, Al Fawaz A, Hemachandran S, Mousa A, Mohamed AG, Al-Obeidan SA, Abu El-Asrar AM.  Ocul Immunol Inflamm. 2015 Oct 15:1-8. [Epub ahead of print] PubMed PMID: 26470690. 
2. Association of total antioxidants level with glaucoma type and severity. Mousa A, Kondkar AA, Al-Obeidan SA, Azad TA, Sultan T, Osman E, Abu-Amero KK. Saudi Med J. 2015 Jun;36(6):671-7. DOI: 10.15537/smj.2015.6.10697. PubMed PMID:25987108
3. Corrigendum: A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. Aung T,……Al-Obeidan SA, et al. Nat Genet. 2015 May 27;47(6):689. DOI: 10.1038/ng0615-689c. PubMed PMID: 26018902.
4. Incidence, efficacy and safety of YAG laser goniopuncture following nonpenetrating deep sclerectomy at a university hospital in Riyadh, Saudi Arabia. Saudi J Ophthalmol. 2015 Apr-Jun;29(2):95-102. doi: 10.1016/j.sjopt.2014.09.015. Epub 2014 Oct 7. PubMed PMID: 25892927; PubMed Central PMCID: PMC4398810.
5. A common variant near TGFBR3 is associated with primary open angle glaucoma. Li Z, Allingham RR,…….Al-Obeidan SA, et al. Hum Mol Genet. 2015 Jul 1;24(13):3880-92. DOI: 10.1093/hmg/ddv128. Epub 2015 Apr 10. PubMed PMID: 2586181
6. A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. Aung T,……Al-Obeidan SA, et al. Nat Genet. 2015 Apr;47(4):387-92. DOI: 10.1038/ng.3226. PubMed PMID: 25706626
7. Long-term evaluation and efficacy and safety of deep sclerectomy in uveitic glaucoma. Saleh A Al-Obeidan, Essam A Osman, Ahmed Mousa, Abdulrahman M Al-Muammar, Ahmed M. Abu El-Asrar. Ocul Immunol Inflamm. 2015 Feb;23(1):82-9. DOI: 10.3109/09273948.2013.870213. Epub 2014 Jan 10. PMID: 24410348
8. Total antioxidant level is correlated with intra-ocular pressure in patients with primary angle closure glaucoma. Abu-Amero KK, Azad TA, Mousa A, Osman EA, Sultan T, Al-Obeidan SA. BMC Res Notes. 2014 Mar 19;7:163. DOI: 10.1186/1756-0500-7-163. PubMed PMID: 24646376
9. Efficacy and safety of deep sclerectomy in childhood glaucoma in Saudi Arabia. Saleh A Al-Obeidan, Essam A Osman, Ahmed S Dewedar, Philippe Kestelyn, Ahmed Mousa. Acta Ophthalmol. 2014; Feb 92(1):65-70. DOI: 10.1111/j.1755-3768.2012.02558.x. PMID: 23241279
10. ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma. Monisha E Nongpiur, Chiea Chuen Khor, Hongyan Jia, Belinda K Cornes, Saleh A Al-Obeidan et al. PLOS Genetics Mar 2014; vol 10(3) :e1004089. DOI: 10.1371/journal.pgen.1004089. PMID: 24603532
11. Efficacy and safety of non-penetrating deep sclerectomy surgery in Saudi patients with uncontrolled open angle glaucoma. Saleh A Al-Obeidan, Ahmed Mousa, Abid Naseem, Khaled K Abu Amero, Essam A Osman. Saudi Med J 2013; vol 34(1):54-61. PMID: 23299160
12. Decreased total antioxidants in patients with primary open angle glaucoma. Khaled K Abu-Amero, Altaf A Kondkar, Ahmed Mousa, Essam A Osman, Saleh A Al-Obeidan. Current Eye Research. 2013;38(9):959-964. DOI: 10.3109/02713683.2013.794246.
13. Association of SOD2 Mutation (c.47T>C) with various primary angle closure glaucoma clinical indices. Khaled K Abu-Amero, Taif Anwar Azad, Ahmed Mousa, Essam A Osman, Tahira Sultan, Saleh A Al-Obeidan. Ophthalmic Genetics 2013. Early Online, 1-4,02013. ISSN:1381-6810 print /1744-5094 online. DOI: 10.3109/13816810.2013.838276.
14. A catalase promoter variant rs1001179 is associated with visual acuity but not with primary angle closure glaucoma in Saudi patients. Khaled K Abu-Amero, Taif Anwar Azad, Ahmed Mousa, Essam A Osman, Tahira Sultan, Saleh A Al-Obeidan. BMC Medical Genetics 2013; 14:84.
15. Analysis of Catalase SNP rs1001179 in Saudi patients with Primary Open Angle Glaucoma. Khaled K Abu-Amero, Altaf A. Kondkar, Ahmed Mousa, Essam A Osman, Saleh A Al-Obeidan. Ophthalmic Genetics. 2013;34(4):223-228. ISSN: 1381-6810 print / 1744-5094 online; DOI: 10.3109/13816810.2013.789534.
16. Association of Mn-SOD Mutation (c.47T>C) with various POAG Clinical Indices. Khaled K Abu-Amero, Altaf A Kondkar, Ahmed Mousa, Essam A Osman, and Saleh A Al-Obeidan. Ophthalmic Genetics 2013. Early Online. 1-6.2013. ISSN: 1381-6810 print / 1744-5094 online. DOI: 10.3109/13816810.2013.796390.
17. Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma.  Vithana EN, Khor CC, Qiao C, Nongpiur ME, George R, Chen LJ, Do T, Abu-Amero K, Huang CK, Low S, Tajudin LS, Perera SA, Cheng CY, Xu L, Jia H, Ho CL, Sim KS, Wu RY, Tham CC, Chew PT, Su DH, Oen FT, Sarangapani S, Soumittra N, Osman EA, Wong HT, Tang G, Fan S, Meng H, Huong DT, Wang H, Feng B, Baskaran M, Shantha B, Ramprasad VL, Kumaramanickavel G, Iyengar SK, How AC, Lee KY, Sivakumaran TA, Yong VH, Ting SM, Li Y, Wang YX, Tay WT, Sim X, Lavanya R, Cornes BK, Zheng YF, Wong TT, Loon SC, Yong VK, Waseem N, Yaakub A, Chia KS, Allingham RR, Hauser MA, Lam DS, Hibberd ML, Bhattacharya SS, Zhang M, Teo YY, Tan DT, Jonas JB, Tai ES, Saw SM, Hon do N, Al-Obeidan SA, Liu J, Chau TN, Simmons CP, Bei JX, Zeng YX, Foster PJ, Vijaya L, Wong TY, Pang CP, Wang N, Aung T. Nat Genet. 2012 Oct;44(10):1142-6. DOI: 10.1038/ng.2390. Epub 2012 Aug 26. PMID: 22922875
18. Lack of association of SNP rs4236601 near CAV1 and CAV2 with POAG in a Saudi cohort.  Abu-Amero KK, Kondkar AA, Mousa A, Osman EA, Al-Obeidan SA. Mol Vis. 2012;18:1960-5. Epub 2012 Jul 18.  [PMID: 22876122]
19. Cytokine and CXC chemokine expression patterns in aqueous humor of patients with presumed tuberculous uveitis.  Abu El-Asrar AM, Struyf S, Kangave D, Al-Obeidan SA, Opdenakker G, Geboes K, Van Damme J. Cytokine. 2012 Aug;59(2):377-81. DOI: 10.1016/j.cyto.2012.04.030. Epub 2012 May 12. PMID: 22583692
20. Screening of CYP1B1 and LTBP2 genes in Saudi families with primary congenital glaucoma: genotype-phenotype correlation. Abu-Amero KK, Osman EA, Mousa A, Wheeler J, Whigham B, Allingham RR, Hauser MA, Al-Obeidan SA. Mol Vis. 2011;17:2911-9. Epub 2011 Nov 12. PMID: 22128238
21. Lack of association between LOXL1 gene polymorphisms and primary open angle glaucoma in the Saudi Arabian population. Abu-Amero KK, Osman EA, Azad MT, Allingham RR, Hauser MA, Al-Obeidan SA. Ophthalmic Genet. 2012 Sep;33(3):130-3. DOI: 10.3109/13816810.2011.575430. Epub 2011 Apr 21. PMID: 21510775
22. Decreased total antioxidants status in the plasma of patients with pseudoexfoliation glaucoma. Abu-Amero KK, Kondkar AA, Mousa A, Osman EA, Al-Obeidan SA. Mol Vis. 2011;17:2769-75. Epub 2011 Oct 25. PMID: 22065931
23. Outcomes of Retreatment after Aborted Laser In Situ Keratomileusis due to Flap Complications. Al-Mezaine HS, Al-Amro SA, Al-Fadda A, Al-Obeidan S. Middle East Afr J Ophthalmol. 2011 Jul;18(3):232-7. doi: 10.4103/0974-9233.84054. PubMed PMID: 21887080; PubMed Central PMCID: PMC3162737.
24. Susceptibility to primary angle closure glaucoma in Saudi Arabia: the possible role of mitochondrial DNA ancestry informative haplogroups. Abu-Amero KK, González AM, Osman EA, Larruga JM, Cabrera VM, Al-Obeidan SA. Mol Vis. 2011;17:2171-6. Epub 2011 Aug 12. PMCID: PMC3156795 
25. Mitochondrial DNA lineages of African origin confer susceptibility to primary open-angle glaucoma in Saudi patients. Abu-Amero KK, González AM, Osman EA, Larruga JM, Cabrera VM, Al-Obeidan SA. Mol Vis. 2011;17:1468-72. Epub 2011 Jun 3.  PMC3110492
26. CXC chemokine expression profiles in aqueous humor of patients with different clinical entities of endogenous uveitis. El-Asrar AM, Al-Obeidan SA, Kangave D, Geboes K, Opdenakker G, Van Damme J, Struyf S. Immunobiology. 2011 Sep;216(9):1004-9. Epub 2011 Apr PMID: 21531038
27. Eurasian and Sub-Saharan African mitochondrial DNA haplogroup influences pseudoexfoliation glaucoma development in Saudi patients. Abu-Amero KK, Cabrera VM, Larruga JM, Osman EA, González AM, Al-Obeidan SA. Mol Vis. 2011 Feb 19;17:543-7. PMID: 21364909
28. Cytokine profiles in aqueous humor of patients with different clinical entities of endogenous uveitis. El-Asrar AM, Struyf S, Kangave D, Al-Obeidan SA, Opdenakker G, Geboes K, Van Damme J. Clin Immunol. 2011 May;139(2):177-84. Epub 2011 Jan 31. PMID: 21334264
29. Intraoperative flap complications in laser in situ keratomileusis with two types of microkeratomes. Hani S. Al-Mezaine, Saleh A. Al-Amro, Saleh Al-Obeidan. Saudi J Ophthalmol. 2011 Jul;25(3):239-43. doi: 10.1016/j.sjopt.2011.04.002. Epub 2011 Apr 23. PMID: 23960931
30. The profile of glaucoma in a Tertiary Ophthalmic University Center in Riyadh, Saudi Arabia. Al-Obeidan, S. A. et al. Saudi Journal of Ophthalmology (2011). 25: 373-379. PMID: 23960951
31. Analysis of LOXL1 polymorphisms in a Saudi Arabian population with pseudoexfoliation glaucoma. Abu-Amero KK, Osman EA, Dewedar AS, Schmidt S, Allingham RR, Al-Obeidan SA. Mol Vis. 2010 Dec 16;16:2805-10. PMID: 21197115
32. Comparison of central corneal thickness measurements using Pentacam and ultrasonic pachymetry in post-LASIK eyes for myopia. Al-Mezaine HS, Al-Amro SA, Kangave D, Al-Obeidan S, Al-Jubair KM. Eur J Ophthalmol. 2010 Sep-Oct;20(5):852-7. PMID: 20815096
33. Controlled Cyclophotocoagulation with diode laser in refractory glaucoma and long term follow up at King Abdulaziz University Hospital, Riyadh. Essam A. Osman, Abdulrahman Al-Muammar, Ahmed Mousa, Hani Al-Mezaine, Saleh A. Al-Obeidan, Saudi Journal of Ophthalmology, Volume 24, Issue 1, January–March 2010, Pages 9-13. PMID: 23960867
34. Migration of reticulated hyaluronic acid implant [SK-GEL] following deep sclerectomy. Al Obeidan SA. Int Ophthalmol. 2010 Jun;30(3):329-31. Epub 2009 Oct 22. PMID: 19847378
35. Refractory Noninfectious Anterior Uveitis Associated With Systemic Mastocytosis. Al-Mezaine HS, Al-Obeidan S, Al-Hakeem MM, Abu El-Asrar AM. J Pediatr Ophthalmol Strabismus. 2009 Oct 2. DOI: 10.3928/01913913-20090918-01. Epub 2009 Oct 2. PMID: 19791718
36. Incidence, management, and visual outcomes of buttonholed laser in situ keratomileusis flaps. Al-Mezaine HS, Al-Amro SA, Al-Obeidan S. J Cataract Refract Surg. 2009 May;35(5):839-45. PMID: 19393882
37. The relationship between central corneal thickness and degree of myopia among Saudi adults. Al-Mezaine HS, Al-Obeidan S, Kangave D, Sadaawy A, Wehaib TA, Al-Amro SA
38. Efficacy and safety of deep sclerectomy in uveitic glaucoma. Al Obeidan SA, Osman EA, Al-Muammar AM, Abu El-Asrar AM. Int Ophthalmol. 2009 Oct;29(5):367-72. Epub 2008 Jun 19.
39. Bilateral acute angle closure glaucoma after hyperopic LASIK correction. Essam A. Osman, Ahmed A. Alsaleh, Turki Al Turki, Saleh A. AL Obeidan. Saudi Journal of Ophthalmology, Volume 23, Issues 3–4, October 2009, Pages 215-217. http://www.sciencedirect.com/science/article/pii/S131945340900037X. PMID: 23960863
40. Nonpenetrating deep sclerectomy. Saleh A Al Obeidan. Expert Review of Ophthalmology, Jun 2009, Vol. 4, No. 3, Pages 299-315.
41. Comparison between central corneal thickness measurements by oculus pentacam and ultrasonic pachymetry. Al-Mezaine HS, Al-Amro SA, Kangave D, Sadaawy A, Wehaib TA, Al-Obeidan S. Int Ophthalmol. 2008 Oct;28(5):333-8. PMID: 17898935
42. Full preoperative panretinal photocoagulation improves the outcome of trabeculectomy with mitomycin C for neovascular glaucoma. Al Obeidan SA, Osman EA, Al-Amro SA, Kangave D, Abu El-Asrar AM. Eur J Ophthalmol. 2008 Sep-Oct;18(5):758-64 PMID: 1885055
43. Chemokines and gelatinases in the aqueous humor of patients with active uveitis. Abu El-Asrar AM, Struyf S, Descamps FJ, Al-Obeidan SA, Proost P, Van Damme J, Opdenakker G, Geboes K. Am J Ophthalmol. 2004 Sep;138(3):401-11 PMID: 15364222
44. Late onset posttraumatic Propionibacterium acnes endophthalmitis. El-Asrar AM, Al-Obeidan SA, Yeboah EA. Eur J Ophthalmol. 2004 Sep-Oct;14(5):442-4 PMID: 1550660
45. Retinal periphlebitis resembling frosted branch angiitis with nonperfused central retinal vein occlusion. Abu El-Asrar AM, Al-Obeidan SA, Abdel Gader AG. Eur J Ophthalmol. 2003 Nov-Dec;13(9-10):807-12. Review PMID: 14700106
46. Sympathetic ophthalmia after complicated cataract surgery and intraocular lens implantation. El-Asrar AM, Al-Obeidan SA. Eur J Ophthalmol. 2001 Apr-Jun;11(2):193-6 PMID: 11456026
47. Post-traumatic endophthalmitis: causative organisms and visual outcome. Abu el-Asrar AM, al-Amro SA, al-Mosallam AA, Al-Obeidan S. Eur J Ophthalmol. 1999 Jan-Mar;9(1):21-31 PMID: 10230588
48. Pars plana vitrectomy in the management of ghost cell glaucoma. Abu el-Asrar AM, Al-Obeidan SA. Int Ophthalmol. 1995;19(2):121-4 PMID: 8586495
49. Transscleral neodymium: YAG laser cyclophotocoagulation for end-stage glaucoma, refractory glaucoma, and painful blind eyes. Al-Ghamdi S, Al-Obeidan S, Tomey KF, al-Jadaan I. Ophthalmic Surg. 1993 Aug;24(8):526-9 PMID: 8233315