Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors

رقم المجلد

2014

رقم الانشاء

مجلة/صحيفة

Bioorganic & Medicinal Chemistry Letters

الصفحات

4557–4567

مزيد من المنشورات

Cancer stem cells CD133 inhibition and cytotoxicity of certain 3-phenylthiazolo[3,2- a ]benzimidazoles: design, direct synthesis, crystal study and in vitro biological evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry

Cancer stem cells (CSCs) have been objects of intensive study since their identification in 1994.

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Synthesis, antimicrobial, anti-biofilm evaluation, and molecular modelling study of new chalcone linked amines derivatives, Journal of Enzyme Inhibition and Medicinal Chemistry

A series of amide chalcones conjugated with different secondary amines were synthesised and characterised by different spectroscopic techniques 1H NMR, 13C NMR, and ESI-MS. They were screened for…

بواسطة Shahenda M. El-Messery, El-Sayed E. Habib, Sarah T. A. Al-Rashood & Ghada

2018

Thiazolo[3,2-a][1,3]diazepine derivatives and pharmaceutical compositions containing the same as anticonvulsant agents and method for their preparation

مرادفات الثياديازولودايزبين - طرق تحضيرها - تركيباتها و فاعليتها كعلاج مبتكر لمرض الصرع

2017

Sara T Al-Rashood

Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors