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Prof. Dr. Shagufta Perveen FRSC-UK, PhD

Professor

Professor

كلية الصيدلة
Room # 57, 3rd Floor, Buil. # 8, Dept. of Pharmacognosy
المنشورات
مقال فى مجلة
2019

New Bioactive Metabolites from the Thermophilic Fungus Penicillium sp. Isolated from Ghamiqa Hot Spring in Saudi Arabia

Taglialatela-Scafati, Shagufta Perveena,⁎ , Jawaher Alqahtania,d , Raha Orfalia , Areej Mohammad Al-Taweela , Hasan Soliman Yusufoglub , Maged Saad Abdel-Kaderb,c , Orazio . 2019

Full length research paper

Anvillea garcinii is a medicinal plant used in the Arab region for intestinal diseases, lungs and liver diseases, digestive problems, and as an anti-diabetic. Repeated chromatographic purifications of A. garcinii leaves led to the isolation of two undescribed guaiane sesquiterpene lactones (1–2), along with four known germacranolides (3–6). The structures of the new compounds were established using spectroscopic (1D, 2D NMR) and spectrometric methods (ESIMS). Compounds 1 and 2 were shown to possess hydroxyl substituents at position 9, a structural feature rarely reported in guaianolide-type sesquiterpenes. The antimicrobial activity of 1–6 was screened against five different gram-positive/negative bacteria and the fungi Candida albicans and C. parapsilosis. Compounds 1 and 2 displayed remarkable antifungal effect against C. albicans and C. parapsilosis and potent antibacterial activities against Staphylococcus aureus. 

نوع عمل المنشور
Fitoterapia, Elsevier
رقم الانشاء
129-134
مزيد من المنشورات
publications

Anvillea garcinii is a medicinal plant traditionally used for the treatment of dysentery, gastrointestinal troubles, hepatitis, lung disease, colds, digestive problems and pulmonary…

بواسطة Shagufta PerveenEmail authorAreej Mohammad Al-TaweelHasan Soliman YusufogluGhada Ahmed FawzyAhmed FoudahMaged Saad Abdel-Kader
2017
publications
بواسطة Author links open overlay panelAreej MohammadAl‑TaweelaMohammadRaishbShaguftaPerveenaGhada AhmedFawzyacAjazAhmaddMushtaq AhmadAnsarieShahidMudassargMajid AhmadGanaie
2017
publications

Anvillea garcinii is a medicinal plant used in the Arab region for intestinal diseases, lungs and liver diseases, digestive problems, and as an anti-diabetic. Repeated chromatographic…

بواسطة Shagufta Perveena,⁎ , Jawaher Alqahtania,d , Raha Orfalia , Areej Mohammad Al-Taweela , Hasan Soliman Yusufoglub , Maged Saad Abdel-Kaderb,c , Orazio Taglialatela-Scafati
2019