Perspective of Feature Selection Techniques in Bioinformatics
The availability of massive amounts of experimental data based on genome-wide association and mass spectroscopy studies have given motivation in recent years to a large effort in developing mathematical, statistical and computational techniques to infer biological models from data. In many bioinformatics problems the number of features is significantly larger than the number of samples (high feature to sample ratio data sets) and feature selection techniques have become an apparent need in many bioinformatics applications. In addition to the large pool of techniques that have already been developed in the data mining fields, specific applications in bioinformatics have led to a wealth of newly proposed techniques. This assessment provides the aware of the possibilities of feature selection, providing a basic taxonomy of feature selection techniques, discussing their use, variety and potential in a number of both common as well as upcoming bioinformatics applications.
Keywords
Bioinformatics; Feature Selection; Text Mining; Wrapper; Genotype analysis.
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